Cancer Genes / edited by Satish Ramalingam.

Format:

Book

Contributor:

Ramalingam, Satish, editor.

Series:

Cancer Genes Series

Cancer Genes Series ; Volume 1

Language:

English

Subjects (All):

Cancer--Genetic aspects.

Cancer.

Physical Description:

1 online resource (428 pages)

Edition:

First edition.

Place of Publication:

Singapore : Bentham Science Publishers Pte. Ltd., 2023.

Summary:

Cancer Genes is a comprehensivelist of the most critical genes known to contribute to cancer imitation andprogression. The book delves into their location on each chromosome, providingvaluable insights into the mechanisms of cancer gene dysregulation and genetic mutationswhich provide cancer cells with an advantage during each stage oftumorigenesis. The reference will familiarize readers with the location of cancergenes and equip them with the necessary information to identify relevant geneexpression targets for research aimed at preventing the disease. The book is divided into two volumes focusing oncancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes13-23 (volume 2). A key features of the book is a detailed reference list for advancedreaders. The compilation is therefore a quick and handy reference on cancercausing genes for researchers, medical professionals, and anyone interested inunderstanding the genetic basis of cancer.

Contents:

Front Cover

Title

Copyright

End User License Agreement

Contents

Foreword

Preface

List of Contributors

Chromosome 1

Ravi Gor1, Saurav Panicker1 and Satish Ramalingam1,*

1. INTRODUCTION

1.1. MUC1: Mucin-1 Chromosome 1

1q22

1.2. NTRK1: Neurotrophic receptor Tyrosine Kinase-1 Location: Chromosome 1

1q23.3

1.3. PBX1: Pre-B-Cell Leukemia Transcription Factor-1 Chromosome 1

1.4. ABL2: Tyrosine Protein Kinase ABL2 Chromosome 1

1q25.2

1.5. Notch2: Neurogenic Locus Notch Homolog Protein-2 Chromosome 1

1p12

1.6. NRAS: NRAS Proto-Oncogene Chromosome 1

1p13.2

1.7. JUN: Jun Proto-Oncogene Chromosome 1

1p32.1

1.8. TAL1: T-Cell Acute Lymphocytic Leukemia Protein-1 Chromosome 1

1p33

1.9. JAK1: Jenus Kinase-1 Chromosome 1

1p31.3

1.10. SFPQ: Splicing Factor, Proline and Glutamine-Rich Chromosome 1

1p34.3

1.11. ARNT: Aryl Hydrocarbon Translocator Chromosome 1

1q21.3

1.12. REG4: Regenerating Islet-Derived Protein-4 Chromosome 1

1.13. CD58: Cluster of Differentiation 58 Chromosome 1

1p13.1

1.14. RAP1A: Ras-Related Protein Rap-1A Chromosome 1

1.15. GSTM3: Glutathione S-Transferase M3C Chromosome 1

1p13.3

1.16. YBX1: Y-Box Binding Protein Chromosome 1

1p34.2

1.17. STMN1: Stahmin-1 Chromosome 1

1p36.11

1.18. WNT4: WNT Family Member 4 Chromosome 1

1p36.12

1.19. E2F2: Transcription Factor E2F2 Chromosome 1

1.20. PARK7: Parkinson Disease Protein-7 Chromosome 1

1p36.23

1.21. ARID1A: AT-Rich Interaction Domain-1A Chromosome 1

1.22. ENO1: Enolase-1 Chromosome 1

1.23. SMYD3: SET and MYND Domain-Containing Protein-3 Chromosome 1

1q44

1.24. TP53BP2: Tumor Suppressor p53 Binding Protein-2 Chromosome 1

1q41

1.25. PDPN: Podoplanin Chromosome 1

1p36.21.

1.26. SHC1: SHC Adaptor Protein-1 Chromosome 1

1.27. MDM4: Mouse Double Minute-4 Chromosome 1

1q32.1

1.28. ADAR: Adenosine Deaminases Acting on RNA Chromosome 1

1.29. HDGF: Hepatoma-Derived Growth Factor Chromosome 1

1q23.1

1.30. MUTYH: mutY DNA Glycosylase Chromosome 1

1p34.1

1.31. SDHB: Succinate Dehydrogenase Iron-Sulfur Subunit B Chromosome 1

1p36.13

1.32. EXO1: Exonuclease-1 Chromosome 1

1q43

1.33. FH: Fumarate Hydratase Chromosome 1

1.34. RHOC: RAS Homolog Gene Family Member C Chromosome 1

1.35. TGFBR3: Transforming Growth Factor-Beta Receptor-3 Chromosome 1

1p22.1

1.36. CCN1: CCN Family Member-1 Chromosome 1

1p22.3

1.37. IL23R: Interleukin 23 Receptor Chromosome 1

1.38. ROR1: Receptor Tyrosine kinase-Like Orphan Receptor-1 Chromosome 1

1.39. PTPRF: Protein Tyrosine Phosphatase Receptor Type-F Chromosome 1

1.40. PUM1: Pumilio-1 Chromosome 1

1q35.2

CONCLUSION

REFERENCES

Chromosome 2

Thilaga Thirugnanam1, Saurav Panicker1 and Satish Ramalingam1,*

1.1. APOB - APOLIPOPROTEIN B CHROMOSOME 2

2P24.1

1.2. BOLL - BOULE HOMOLOG, RNA BINDING PROTEIN CHROMOSOME 2

2Q33.1

1.3. BUB1 - BUB1 MITOTIC CHECKPOINT SERINE/THREONINE KINASE CHROMOSOME 2

2Q13

1.4. CCL20 - C-C MOTIF CHEMOKINE LIGAND 20 CHROMOSOME 2

2Q36.3

1.5. CFLAR - CASP8 AND FADD-LIKE APOPTOSIS REGULATOR CHROMOSOME 2

1.6. CREB1 - CAMP RESPONSIVE ELEMENT BINDING PROTEIN 1 CHROMOSOME 2

2Q33.3

1.7. CTLA4 - CYTOTOXIC T-LYMPHOCYTE ASSOCIATED PROTEIN 4 CHROMOSOME 2

2Q33.2

1.8. CXCR4 - C-X-C MOTIF CHEMOKINE RECEPTOR 4 CHROMOSOME 2

2Q22.1

1.9. CYP1B1 - CYTOCHROME P450 FAMILY 1 SUBFAMILY B MEMBER 1 CHROMOSOME 2

2P22.2

1.10. DDX1 - DEAD-BOX HELICASE 1 CHROMOSOME 2

2P24.3.

1.11. DNMT3A - DNA METHYL TRANSFER ASE 3 ALPHA CHROMOSOME 2

2P23.3

1.12. EFEMP1 - EGF CONTAINING FIBULIN EXTRACELLULAR MATRIX PROTEIN 1 CHROMOSOME 2

2P16.1

1.13. EPCAM - EPITHELIAL CELL ADHESION MOLECULE CHROMOSOME 2

2P21

1.14. ERBB4 - ERB-B2 RECEPTOR TYROSINE KINASE 4 CHROMOSOME 2

2Q34

1.15. FHL2 - FOUR AND A HALF LIM DOMAINS 2 CHROMOSOME 2

2Q12.2

1.16. FOSL2 - FOS LIKE 2, AP-1 TRANSCRIPTION FACTOR SUBUNIT CHROMOSOME 2

2P23.2

1.17. FRZB - FRIZZLED RELATED PROTEIN CHROMOSOME 2

2Q32.1

1.18. FZD7 - FRIZZLED CLASS RECEPTOR 7 CHROMOSOME 2

1.19. GREB1 - GROWTH REGULATING ESTROGEN RECEPTOR BINDING 1 CHROMOSOME 2

2P25.1

1.20. GLI2 - GLI FAMILY ZINC FINGER 2 CHROMOSOME 2

2Q14.2

1.21. HDAC4 - HISTONE DEACETYLASE 4 CHROMOSOME 2

2Q37.3

1.22. HOXD10 - HOMEOBOX D10 CHROMOSOME 2

2Q31.1

1.23. ID2 - INHIBITOR OF DNA BINDING 2 CHROMOSOME 2

1.24. IDH1 - ISOCITRATE DEHYDROGENASE (NADP (+)) 1 CHROMOSOME 2

1.25. IL1B - INTERLEUKIN 1 BETA CHROMOSOME 2

2Q14.1

1.26. ING5 - INHIBITOR OF GROWTH FAMILY MEMBER 5 CHROMOSOME 2

1.27. IRS1- INSULIN RECEPTOR SUBSTRATE 1 CHROMOSOME 2

1.28. MEIS1 - MEIS HOMEOBOX 1 CHROMOSOME 2

2P14

1.29. MYCN - MYCN PROTO-ONCOGENE, BHLH TRANSCRIPTION FACTOR CHROMOSOME 2

2P24.3

1.30. NCOA1 - NUCLEAR RECEPTOR COACTIVATOR 1 CHROMOSOME 2

1.31. NR4A2 - NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 CHROMOSOME 2

2Q24.1

1.32. ODC1 - ORNITHINE DECARBOXYLASE 1 CHROMOSOME 2

1.33. PAX3 - PAIRED BOX 3 CHROMOSOME 2

2Q36.1

1.34. PAX8 - PAIRED BOX 8 CHROMOSOME 2

1.35. RALB - RAS LIKE PROTO-ONCOGENE B CHROMOSOME 2

1.36. RANBP2 - RAN BINDING PROTEIN 2 CHROMOSOME 2

1.37. REG1A - REGENERATING FAMILY MEMBER 1 ALPHA CHROMOSOME 2

2P12.

1.38. REL - REL PROTO-ONCOGENE, NF-KB SUBUNIT CHROMOSOME 2

1.39. REV1 - REV1 DNA DIRECTED POLYMERASE CHROMOSOME 2

2Q11.2

1.40. RHOB - RAS HOMOLOG FAMILY MEMBER B CHROMOSOME 2

1.41. ROCK2 - RHO-ASSOCIATED COILED-COIL CONTAINING PROTEIN KINASE 2 CHROMOSOME 2

1.42. RRM2 - RIBONUCLEOTIDE REDUCTASE REGULATORY SUBUNIT M2 CHROMOSOME 2

1.43. SDC1 - SYNDECAN 1 CHROMOSOME 2

1.44. SOX11 - SRY-BOX TRANSCRIPTION FACTOR 11 CHROMOSOME 2

2P25.2

1.45. STAT1 - SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 CHROMOSOME 2

2Q32.2

1.46. SUMO1 - SMALL UBIQUITIN-LIKE MODIFIER 1 CHROMOSOME 2

1.47. TCF7L1 - TRANSCRIPTION FACTOR 7 LIKE 1 CHROMOSOME 2

2P11.2

1.48. TIA1 - TIA1 CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN CHROMOSOME 2

2P13.3

1.49. TRPM8 - TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M, MEMBER 8 CHROMOSOME 2

2Q37.1

1.50. TWIST2 - TWIST FAMILY BHLH TRANSCRIPTION FACTOR 2 CHROMOSOME 2

Chromosome 3

Saurav Panicker1 and Satish Ramalingam1,*

1.1. BCL6: B-Cell Lymphoma 6 Chromosome 3

3q27.3

1.2. RAF1: Rapidly Accelerated Fibrosarcoma, Chromosome 3

3p25.2

1.3. TFG: Tropomyosin-Receptor Kinase Fused Gene Chromosome 3

3q12.2

1.4. SRGAP3: SLIT-ROBO Rho GTPase-Activating Protein 3 Chromosome 3

3p25.3

1.5. GATA2: GATA Binding Protein 2 Chromosome 3

3q21.3

1.6. RPN1: Ribophorin I Chromosome 3

1.7. CNBP: Cellular Nucleic Acid-Binding Protein Chromosome 3

1.8. FHIT: Fragile Histidine Triad Diadenosine Triphosphatase Chromosome 3

3p14.2

1.9. PPARG: Peroxisome Proliferator-Activated Receptor Gamma Chromosome 3

1.10. MECOM: MDS1 and EVI1 Complex Locus Chromosome 3

3q26.2.

1.11. MITF - Melanocyte Inducing Transcription Factor Chromosome 3

3p13

1.12. FOXP1: Forkhead Box Protein P1 Chromosome 3

1.13. PBRM1: Polybromo-1 Chromosome 3

3p21.1

1.14. BAP1: BRCA1 Associated Protein 1 Chromosome 3

1.15. NCKIPSD: NCK Interacting Protein with SH3 Domain Chromosome 3

3p21.31

1.16. SETD2: Set Domain Containing 2 Chromosome 3

1.17. CTNNB1 Gene: Catenin Beta 1 Chromosome 3

3p22.1

1.18. MYD88: Myeloid Differentiation Primary Response 88 Chromosome 3

3p22.2

1.19. CBLB: Cbl Proto-Oncogene B Chromosome 3

3q13.11

1.20. FOXL2: Forkhead Box Protein L2 Chromosome 3

3q22.3

1.21. WWTR1: WW Domain Containing Transcription Regulator 1 Chromosome 3

3q25.1

1.22. GMPS: Guanine Monophosphate Synthase Chromosome 3

3q25.31

1.23. MLF1: Myeloid Leukemia Factor 1 Chromosome 3

3q25.32

1.24. PIK3CA: Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Chromosome 3

3q26.32

1.25. SOX2: Sex-Determining Region Y [SRY]-Box Rranscription Factor 2 Chromosome 3

3q26.33

1.26. ETV5: ETS Variant Transcription Factor 5 Chromosome 3

3q27.2

1.27. EIF4A2: Eukaryotic Translation Initiation Factor 4A, Isoform 2 Chromosome 3

1.28. LPP: Lipoma Preferred Partner Chromosome 3

3q27.3-q28

1.29. RASSF1: Ras Association Domain-Containing Protein 1 Chromosome 3

1.30. MLH1: MutL Homolog 1 Chromosome 3

1.31. VHL: Von Hippel-Lindau Chromosome 3

1.32. XPC: Xeroderma Pigmentosum Complementation Group C [XP Complex Subunit C] Chromosome 3

3p25.1

1.33. FANCD2: Fanconi Anemia Complementation Group D2 Protein Chromosome 3

1.34. POU1F1: POU Class 1 Homeobox 1 Chromosome 3

3p11.2

1.35. EPHA3: EPH Receptor A3 Chromosome 3

3p11.1.

1.36. ROBO1: Roundabout Guidance Receptor 1 Chromosome 3.

Notes:

Description based on publisher supplied metadata and other sources.

Description based on print version record.

Includes bibliographical references.

ISBN:

9789815080292

9815080296

OCLC:

1394117397