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Phenolic compounds in health and disease / edited by Robert C. Linn.
- Format:
- Book
- Series:
- Food Science and Technology
- Language:
- English
- Subjects (All):
- Phenols--Physiological effect.
- Phenols.
- Physical Description:
- 1 online resource (238 pages)
- Place of Publication:
- New York, New York : Nova Science Publishers, Incorporated, [2021]
- Summary:
- "Phenolic compounds are structures found in plant-based foods that play an important role in regulating health and disease. Accordingly, this book presents seven chapters that explore phenolic compounds from a variety of perspectives. Chapter One addresses the current knowledge about the presence of phenolic compounds in plants, their bioavailability and protective effects of interest for diabetes mellitus. Chapter Two describes the Bignoniaceae family and Handroanthus impetiginosus, as well as the main groups of phenolic compounds reported for this species and their main biological activities. Chapter Three highlights some scientific evidence corroborating the role of polyphenols in the prevention and treatment of cancer. Chapter Four presents the results of a study that indicate that L. leucocephala calli are promising biotechnological products for obtaining phenolic compounds in vitro. Chapter Five details a study that assessed the phenolic compound content and antioxidant and antibacterial activities of extracts and fractions of Bauhinia holophylla. Chapter Six evaluates the production of phenolic compounds in cell suspensions of B. variegate. Finally, Chapter Seven provides an insight on the anti-inflammatory activities of galangin through attenuation of allergic inflammation, regulation of PPARy pathway, inhibition of ERK, NF-kappaB, PI3K/AKT and NLRP3 signaling, interplaying of MAPK signaling cascade, and through activation of Nrf2 signaling in animal models"-- Provided by publisher.
- Contents:
- Intro
- Contents
- Preface
- Chapter 1
- Health Benefits of Phenolic Compounds against Diabetes: Recent Advances
- Abstract
- Introduction
- Phenolics Structure and Dietary Sources
- Non-Flavonoids
- Phenolic Acids
- Coumarins
- Lignans
- Stilbenes
- Flavonoids
- Flavonols
- Flavan-3-ols
- Flavones
- Flavanones
- Isoflavones
- Flavanonols
- Anthocyanidins
- Phenolics Extraction
- Phenolics Bioavailability and Metabolism
- Diabetes Mellitus
- Antidiabetic Potential of Phenolic Compounds
- In Vitro and In Vivo Non-Clinical Studies
- Human Studies and Clinical Trials
- Diet Rich in Phenolic Compounds
- Isolated Phenolic Compounds
- Conclusion
- Acknowledgments
- References
- Biographical Sketches
- Chapter 2
- Phenolic Compounds and Biological Activity of Handroanthus impetiginosus (Bignoniaceae)
- Bignoniaceae Juss
- Handroanthus mattos
- Handroanthus impetiginosus
- Some Phenolic Compounds from Handroanthus Impetiginosus and Their Biological Activities
- Naphtoquinones
- β-Lapachone
- Furanonaphthoquinones
- Other Phenolic Compounds
- Chapter 3
- Cancer Prevention and Management through Phenolic Compounds
- The Nature of Phenolic Compounds
- Antioxidant Properties of Phenolic Compounds
- Phenolic Compounds as Cancer Prevention and Therapy
- Breast Cancer
- Prostate Cancer
- Gastric Cancer
- Colorectal Cancer
- Lung Cancer
- Liver Cancer
- Innovative Cancer Therapy
- Chapter 4
- Production of Phenolic Compounds in Leucaena leucocephala Calli
- Methods
- Chemicals
- Plant Material
- In Vitro Germination
- Callus Induction
- Phenols and Flavonoids Total Content
- Hydroethanolic Extract Preparation
- Total Phenol Content.
- Total Flavonoid Content
- Data Analysis
- Results and Discussion
- In vitro Germination
- Chapter 5
- Phenolic Compounds and Antioxidant and Antibacterial Activities of Bauhinia holophylla (Fabaceae: Cercideae)
- Matherial and Methods
- Preparation and Fractionation of Extracts
- Total Phenol and Flavonoid Content
- Determination of Antioxidant Activity
- Microorganisms
- Determination of the Minimum Inhibitory Concentration (MIC)
- Statistical Analyses
- Results
- Characterization of Extracts and Fractions
- Total Phenol and Flavonoid Content and Antioxidant Activity
- Antibacterial Activity of Extracts and Fractions
- Discussion
- Chapter 6
- Production of Phenolic Compounds in Cell Suspensions of Bauhinia variegata L. (Fabaceae)
- Callus Induction and Growth
- Cell Suspensions Culture
- Cell Viability
- Total Phenol Content
- Total Flavonoid Content
- Chapter 7
- Galangin - A Phenolic Compound with Diverse Anti-Inflammatory Activities
- Anti-Inflammatory Activity of Galangin
- Attenuation of Allergic Inflammation
- Regulation of PPARγ Pathway
- Inhibition of ERK, NF-KappaB, PI3K/AKT and NLRP3 Signalling
- Interplaying of MAPK Signalling Cascade
- Activation of Nrf2 Signaling
- Index
- Blank Page.
- Notes:
- Description based on print version record.
- Includes bibliographical references and index.
- ISBN:
- 1-68507-137-6
- 9781685071370
- OCLC:
- 1267337480
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