Methods for Preclinical Evaluation of Bioactive Natural Products / edited by Ipek Suntar, Davide Barreca, and Luigi Milella.

Format:

Book

Author/Creator:

Suntar, Ipek, Author.

Contributor:

Suntar, Ipek, editor.

Barreca, Davide, editor.

Milella, Luigi, editor.

Language:

English

Subjects (All):

Clinical chemistry.

Physical Description:

1 online resource (314 pages)

Edition:

First edition.

Place of Publication:

Singapore : Bentham Science Publishers Pte. Ltd., 2023.

Summary:

Natural products have dominated our lives since ancient times. Today, they are an inexhaustible source of new medications for disease treatment. The practice of evaluating bioactive compounds extracted from natural sources has also advanced significantly, prompting a need to understand current methods to identify and evaluate them. This book covers basic scientific aspects of preclinical research on natural products for specific conditions and diseases. These include aging, gynecological disorders, inflammatory disorders, renal disorders and cardiovascular disorders. Each of the 10 book chapters give a structured overview on preclinical methods on the etiology of diseases, natural products as the materials for the bioassays, extract types, concentration of the extracts/compounds for in vitro and in vivo assays, preparation of the test materials, application of the test materials, step-by-step methods and related calculations. The book is intended as a quick reference for natural product researchers, pharmacists and postgraduate students in pharmacognosy. Medical doctors working in preclinical research on natural products will also benefit from the information provided.

Contents:

Cover

Title

Copyright

End User License Agreement

Contents

Preface

List of Contributors

Antioxidant Activity Methods

Immacolata Faraone1,2,†, Daniela Russo1,2,†, Fabiana Labanca1, Ludovica Lela1, Maria Ponticelli1, Chiara Sinisgalli1,2 and Luigi Milella1,*

INTRODUCTION

PRECLINICAL ACTIVITY ASSESSMENT OF NATURAL PRODUCTS ON RELATED ACTIVITY

In vitro Assay Procedures

Cuprac Assay

Aim

Principle

Materials and Equipments Required

Reagents Required

Protocol

Calculations

DPPH Scavenging Activity

FRAP Assay

Materials and Equipments Required Generated by AI.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

Description based on print version record.

ISBN:

9789815123043

9815123041

OCLC:

1390917988