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Fields virology: RNA viruses - Volume 3 / editors-in-chief, Peter M. Howley, David M. Knipe ; associate editors, Jeffrey I. Cohen [and three others].
- Format:
- Book
- Language:
- English
- Subjects (All):
- Virology.
- RNA viruses.
- Virus diseases.
- Viruses.
- Physical Description:
- 1 online resource
- Edition:
- Seventh edition.
- Place of Publication:
- Philadelphia : Wolters Kluwer, [2023]
- Summary:
- Now in four convenient volumes, Field's Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field's Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field.Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
- Contents:
- Intro
- Half Title
- Title
- Copyright
- Contributors
- Preface
- Introduction
- Contents
- 1 Rhinoviruses
- History
- Infectious Agent
- Classification
- Physical Characteristics
- Pathogenesis and Pathology
- Entry Into the Host
- Site of Primary Replication
- Spread
- Cell and Tissue Tropism
- Immune Response
- Release From Host and Mode of Transmission
- Virulence
- Persistence
- Epidemiology
- Age
- Morbidity
- Origin and Spread of RV Infections
- Prevalence and Seroepidemiology
- Genetic Diversity of Virus
- Clinical Features
- Diagnosis
- Differential
- Laboratory
- Prevention and Control
- Perspective
- 2 Hepatoviruses
- Hepatovirus Classification and Diversity
- Genome Structure
- Genome Organization
- 5′ UTR Structure and Function
- Polyprotein-Coding RNA
- 3′ UTR Structure and Function
- HAV Proteins
- Nomenclature
- P1 Capsid Proteins
- P2 Proteins: 2B and 2C
- P3 Proteins: 3A, 3B (VPg), 3Cpro, and 3Dpol
- Morphology and Properties of Hepatovirus Virions
- Infectious Extracellular Virions
- Naked Nonenveloped Virions (nHAV)
- Quasi-enveloped Virions (eHAV)
- Replication Cycle
- Attachment, Entry, and Uncoating
- Hepatovirus Translation
- Polyprotein Processing
- RNA Replication
- Capsid Assembly
- RNA Packaging
- Quasi-envelopment and Release
- Pathogenesis
- Host Range
- Tropism
- Animal Models
- Steps in HAV Pathogenesis
- Cell-Intrinsic and Innate Immune Host Responses to HAV
- Humoral Immune Responses to HAV Infection
- Cellular Immune Responses to HAV Infection
- Immunity
- Mechanisms of Liver Injury
- Transmission
- Incidence and Geographic Distribution of HAV Infection
- Clinical Manifestations of HAV Infection
- Management of Hepatitis A
- General Measures
- Passive Immunoprophylaxis.
- Hepatitis A Vaccines
- Perspectives
- Acknowledgments
- 3 Astroviruses
- Virion Structure and Composition
- Genome Structure and Organization
- ORF1a and ORF1b
- ORF2
- ORFX
- Stages of Replication
- Attachment and Entry
- Uncoating
- Translation
- Transcription/Replication
- Assembly and Release
- Entry Into the Host and Primary Site of Replication
- Release From Host and Transmission
- Virulence and Persistence
- Origin and Spread of Epidemics
- Treatment
- Vaccines
- 4 Rubella Virus
- Morphology and Physicochemical Properties of the Virion
- Biological Characteristics
- Structure and Organization of the Genome
- Replication Strategy
- Virus Assembly and Secretion
- RUBV Persistence
- Animal Models of Rubella Virus Infection
- Antigenic Composition and Determinants
- Incidence
- Molecular Epidemiology
- Acute Rubella
- Congenital Rubella Syndrome
- 5 Arteriviruses
- History and Classification of Arteriviruses
- Virion Structure
- The Arterivirus Replication Cycle
- Replication in Cultured Cells
- Genome Translation and Replication
- Synthesis and Translation of Subgenomic mRNAs
- Arterivirus Proteinases and Posttranslational Processing of the Replicase
- Replicase Proteins and the Replication Complex
- Assembly and Release.
- Major Structural Proteins
- Minor Structural Proteins
- Arterivirus-Host Cell Interactions
- Pathogenesis and Pathology of Arterivirus Infections
- Site of Primary Replication, Spread, and Cell and Tissue Tropism
- Immune Responses and Immune Evasion
- Release From the Host and Transmission
- EAV
- PRRSV
- LDV
- SHFV
- WPDV
- Disease Control
- 6 Bornaviridae
- Taxonomy
- The Virion
- Morphology and Physical Characteristics
- Genome and Coding Strategy
- Proteins
- Cycle of Infection
- Transcription, Replication, and Gene Expression
- Bornavirus Infection in Mammals
- Borna Disease
- Human Infections
- Bornavirus Infection in Avians
- Epidemiology, Geographic Distribution, and Host Range
- Clinical Signs and Seroprevalence
- Route of Infection and Transmission
- Gross Findings and Histopathology
- Models of Bornavirus Infection
- Cell Culture Models
- Infection in Mammals
- Diagnosis of Bornavirus Infection
- Differential Diagnoses
- Intra Vitam Diagnosis
- Postmortem Diagnosis
- Therapy and Control
- Vaccination
- Therapeutics
- Perspectives and Public Health Considerations
- 7 Rhabdoviridae
- Lyssaviruses
- Vesiculoviruses
- Ephemeroviruses
- Novirhabdoviruses
- Sigma Virus
- Genome Organization and Encoded Proteins
- The Nucleoprotein
- The Phosphoprotein
- The Matrix Protein
- The Glycoprotein
- The Large Polymerase Protein
- Mechanism of Attachment
- Mechanism of Penetration
- Uncoating and Primary Transcription
- Genome Replication
- Secondary Transcription.
- Viral Replication Compartment
- Assembly of Progeny Virions
- Molecular Genetics of Rhabdoviruses
- Defective Interfering Particles
- Genetic Engineering of Rhabdoviruses
- Molecular and Cellular Basis of Pathogenesis
- Induction and Suppression of Host Antiviral Responses
- Induction of Cytopathic Effects
- Mouse Models of Rhabdovirus Infection
- Entry and Site of Initial Replication
- Virus Spread and Tissue Tropism
- Immune Responses Involved in Recovery From Rhabdovirus Infection
- Immune Response to Vesiculovirus Infection
- Immune Response to Lyssavirus Infection
- Determinants of Viral Virulence
- Epidemiology of Rhabdovirus Infections
- Epidemiology of Lyssavirus Infections
- Epidemiology of Vesiculovirus Infections
- Epidemiology of Ephemerovirus Infections
- Epidemiology of Novirhabdovirus Infections
- Clinical Features of Rhabdovirus Infections
- Lyssavirus Infections
- Vesiculovirus Infections
- Ephemerovirus Infections
- Novirhabdovirus Infections
- Diagnosis of Rhabdovirus Infections
- Prevention and Control of Rhabdovirus Infections
- Lyssavirus Infections in Humans
- Control of Rabies in Animals
- Control of Vesiculovirus Infections
- Control of Ephemerovirus Infections
- Control of Novirhabdovirus Infections
- 8 Mumps Virus
- Virion Morphology and Structure
- Genomic Organization
- Virus Proteins and Replication
- Virus Infection of Host Cells
- Pathology and Pathogenesis
- Infection in Experimental Animals
- Infection in Humans
- Molecular Basis of Virulence
- Immune Responses
- Humoral Immunity
- Cell-Mediated Immunity
- Morbidity and Mortality.
- Origin and Spread of Epidemics
- New Epidemiologic Approaches
- Clinical Diagnosis
- Laboratory Diagnosis
- Differential Diagnosis
- Vaccines and Adverse Events
- Vaccine Use
- 9 Measles Virus
- Propagation and Assay in Cell Culture
- Evolution, Antigenic Composition, and Strain Variation
- Natural (Wild Type) Measles
- Persistent Infection
- Veterinary Correlates
- Experimental Infection in Animals
- Classic Measles
- Subacute Sclerosing Panencephalitis
- Classic Measles and Its Complications
- Atypical Measles
- Measles in the Immunocompromised Host
- Isolation or Detection of Virus
- Detection of Antibody
- Prevention
- Prospects for Eradication
- 10 Respiratory Syncytial Virus and Metapneumovirus
- Virion
- RNA
- Replicative Cycle
- Propagation In Vitro
- Genetics and Reverse Genetics
- Infection of Animals With HRSV and HMPV
- Antigenic Subgroups and Genotypes
- Animal Viruses
- Antigens
- Innate Immunity and Inflammation
- Antibodies
- T Lymphocytes
- Viral Evasion of Host Immunity
- Infection of Infants and Young Children
- Infection of Adults
- Other High-Risk Populations
- The Yearly HRSV Pandemic
- Treatment and Prevention
- 11 Orthoreoviruses
- Basic Features of the Reoviridae.
- Discovery of Mammalian Reoviruses.
- Notes:
- Includes bibliographical references and index.
- Description based on print version record.
- ISBN:
- 9781975112615
- 197511261X
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