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End-stage renal disease and depression : a systematic review / Karli Kondo [and four others].
Connect to full text Available online
View online- Format:
- Book
- Government document
- Author/Creator:
- Kondo, Karli, author.
- Series:
- Evidence-based synthesis program (Series)
- Evidence synthesis program
- Language:
- English
- Subjects (All):
- Depression, Mental--Diagnosis--United States.
- Depression, Mental.
- Depression, Mental--Treatment--United States.
- Chronic renal failure--United States.
- Chronic renal failure.
- Veterans--Medical care--United States.
- Veterans.
- Depressive Disorder--diagnosis.
- Depression--diagnosis.
- Kidney Failure, Chronic--complications.
- Mass Screening--methods.
- Depressive Disorder--therapy.
- Depression--therapy.
- Comparative Effectiveness Research.
- Depression, Mental--Diagnosis.
- Depression, Mental--Treatment.
- Veterans--Medical care.
- United States.
- Medical Subjects:
- Depressive Disorder--diagnosis.
- Depression--diagnosis.
- Kidney Failure, Chronic--complications.
- Mass Screening--methods.
- Depressive Disorder--therapy.
- Depression--therapy.
- Comparative Effectiveness Research.
- Physical Description:
- 1 online resource (vi, 101 pages) : illustrations (some color).
- Other Title:
- ESRD and depression
- Place of Publication:
- Washington, DC : Department of Veterans Affairs, Veterans Health Administration, Health Services Research & Development Service, 2020.
- Summary:
- AIM: We conducted a systematic review to evaluate the performance characteristics of screening tools for depression in Veterans with end-stage renal disease (ESRD), and to better understand the impact, benefits, and harms of depression screening and subsequent treatment for depression. METHODS: We searched electronic databases, clinical trial registries, and reference lists through April 2019 for diagnostic accuracy studies of depression tools for patients with ESRD and for trials examining the effectiveness of interventions for the treatment of depression in patients with ESRD. We abstracted data on study design, interventions, and outcomes. Dual assessment of a study's full text, quality, and strength of evidence (SOE) was agreed upon by consensus using pre-specified criteria. RESULTS: We included 20 treatment RCTs and 16 diagnostic accuracy studies. The best-studied tool was the Beck Depression Inventory-II (BDI-II). Across 4 BDI-II studies, a cutoff of ≥16 provides the best balance between sensitivity and specificity. The BDI-II performed reasonably well when compared to a gold standard clinical interview. SSRIs were the most studied type of drug and the evidence was largely insufficient. We found moderate SOE that long-term, high-dose Vitamin D3 is ineffective for reducing depression severity. Cognitive behavioral therapy (CBT) is more effective than (undefined) psychotherapy and placebo for depression improvement and quality of life (low SOE), and acupressure is more effective than treatment as usual (TAU) or sham to reduce depression severity (low SOE). CONCLUSION: There is limited research evaluating the diagnostic accuracy of most screening tools for depression in patients with ESRD. The BDI-II with a cutoff of ≥16 provides a good balance of sensitivity and specificity. More research is needed to support the use of other tools. We found low SOE that CBT, sertraline, and acupressure may be beneficial. There is moderate SOE that high-dose Vitamin D3 is ineffective. More research is needed.
- Notes:
- "January 2020."
- Includes bibliographical references (pages 75-80).
- Description based on online resource; title from PDF cover (VA, viewed February 19, 2021).
- OCLC:
- 1237044285
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