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Nutritional supplements for age-related macular degeneration : a systematic review / prepared for, Department of Veterans Affairs, Veterans Health Administration, Health Services Research & Development Service ; prepared by, Evidence-based Synthesis Program (ESP) Center, Portland VA Medical Center ; investigators, Devan Kansagara [and others].
Connect to full text Available online
View online- Format:
- Book
- Government document
- Author/Creator:
- Kansagara, Devan, author.
- Series:
- Online access: NCBI NCBI Bookshelf.
- Language:
- English
- Subjects (All):
- Retinal degeneration--Diet therapy--United States.
- Retinal degeneration.
- Dietary supplements--United States.
- Dietary supplements.
- Outcome assessment (Medical care)--United States.
- Outcome assessment (Medical care).
- Macular Degeneration--diet therapy.
- Macular Degeneration--prevention & control.
- Carotenoids--therapeutic use.
- Antioxidants--therapeutic use.
- Fatty Acids, Omega-3--therapeutic use.
- Dietary Supplements.
- United States.
- Medical Subjects:
- Macular Degeneration--diet therapy.
- Macular Degeneration--prevention & control.
- Carotenoids--therapeutic use.
- Antioxidants--therapeutic use.
- Fatty Acids, Omega-3--therapeutic use.
- Dietary Supplements.
- Genre:
- technical reports.
- Technical reports
- Technical reports.
- Physical Description:
- 1 online resource (iv, 43 pages) : illustrations
- Place of Publication:
- Washington, DC : Department of Veterans Affairs, Veterans Health Administration, Health Services Research & Development Service, 2012.
- Summary:
- Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in the developed world. In 2004, AMD affected 1.75 million persons in the United States, a number that is expected to rise to nearly 3 million by 2020 due to the aging of the population. The severity of macular degeneration ranges from Category 1 (least severe) to Category 4 (most severe), and "advanced AMD" is defined as having geographic atrophy involving the center of the macula or features of choroidal neovascularization. Observational studies suggest that people with dietary intakes higher in various carotenoids, antioxidants and omega-3 fatty acids have a lower risk of developing AMD. This has led to several supplementation trials designed to examine the ability of nutritional supplement with carotenoids, antioxidants, or omega-3 fatty acids to prevent the progression of AMD. Our report focuses on the evidence documenting the potential benefits and harms of certain dietary supplements in patients with AMD. We conducted a systematic review of published literature to address the following key questions: In patients with age-related macular degeneration, do nutritional supplements containing carotenoids, antioxidants, or omega-3 fatty acids alone or in combination prevent functional visual loss? In adult populations, what are the harms of carotenoid, antioxidant, and omega-3 fatty acid supplementation?
- Notes:
- "Evidence-based synthesis program."
- "January 2012."
- Includes bibliographical references (pages 29-32).
- Description based on online resource; title from PDF cover (VA, viewed April 23, 2021).
- OCLC:
- 794257303
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