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The diagnosis, evaluation, and management of von Willebrand disease.
- Format:
- Book
- Government document
- Series:
- NIH publication ; no. 08-5832.
- NIH publication ; no. 08-5832
- Language:
- English
- Subjects (All):
- Blood coagulation disorders--Diagnosis.
- Blood coagulation disorders.
- Blood--Diseases.
- Blood.
- Hemorrhage.
- von Willebrand Diseases--diagnosis.
- von Willebrand Diseases--therapy.
- Biomedical Research--methods.
- Hematologic Diseases.
- Medical Subjects:
- von Willebrand Diseases--diagnosis.
- von Willebrand Diseases--therapy.
- Biomedical Research--methods.
- Hematologic Diseases.
- Hemorrhage.
- Physical Description:
- 1 online resource.
- Other Title:
- Von Willebrand disease
- Place of Publication:
- [Bethesda, MD] : U.S. Dept. of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, [2007]
- Summary:
- Von Willebrand disease (VWD) is an inherited bleeding disorder that is caused by deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and also binds and stabilizes blood clotting factor VIII (FVIII) in the circulation. Therefore, defects in VWF can cause bleeding by impairing platelet adhesion or by reducing the concentration of FVIII. The VWD diagnosis and management guidelines from the U.S. Expert Panel are based on review of published evidence as well as expert opinion. Users of these guidelines should be aware that individual professional judgment is not abrogated by recommendations in these guidelines. These guidelines for diagnosis and management of VWD were developed for practicing primary care and specialist clinicians, including family physicians, internists, obstetrician-gynecologists, pediatricians, and nurse-practitioners, as well as hematologists and laboratory medicine specialists.
- Notes:
- Title from PDF title page.
- "December 2007."
- "Full report"--Cover.
- Includes bibliographical references.
- OCLC:
- 425819960
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