2 options
Small intestine and combined liver-small intestine transplantation / S. Steven Hotta.
- Format:
- Book
- Government document
- Author/Creator:
- Hotta, S. Steven
- Series:
- Health technology review ; no. 5.
- AHCPR pub. ; no. 93-0067.
- Health technology review ; no. 5
- AHCPR pub. ; no. 93-0067
- Language:
- English
- Subjects (All):
- Intestine, Small--Transplantation.
- Intestine, Small.
- Liver--Transplantation.
- Liver.
- Combined modality therapy.
- Outcome assessment (Medical care).
- Surgery--Complications.
- Surgery.
- Human beings.
- Intestine, Small--transplantation.
- Liver Transplantation.
- Short Bowel Syndrome--surgery.
- Combined Modality Therapy.
- Follow-Up Studies.
- Graft Rejection--prevention & control.
- Immunosuppressive Agents--therapeutic use.
- Liver Diseases--surgery.
- Outcome Assessment, Health Care.
- Postoperative Complications.
- Short Bowel Syndrome--etiology.
- Humans check tag.
- United States.
- Homo sapiens (species).
- Medical Subjects:
- Intestine, Small--transplantation.
- Liver Transplantation.
- Short Bowel Syndrome--surgery.
- Combined Modality Therapy.
- Follow-Up Studies.
- Graft Rejection--prevention & control.
- Immunosuppressive Agents--therapeutic use.
- Liver Diseases--surgery.
- Outcome Assessment, Health Care.
- Postoperative Complications.
- Short Bowel Syndrome--etiology.
- Humans check tag.
- United States.
- Physical Description:
- 1 online resource
- Place of Publication:
- [Rockville, Md.] : Agency for Health Care Policy and Research, Office of Health Technology Assessment, [1993]
- Summary:
- The reacquisition of bowel functions by transplantation of the small intestines was demonstrated to be technically feasible in dogs in 1966. However, unlike the successful transplantation of the heart, lung, liver, and kidney, transplantation of the small bowel in humans was unsuccessful through the 1980s, mainly because of the failure of immunosuppressive therapy to prevent graft rejections and graft versus host disease. Typically, reports described stormy postoperative courses for small intestine graft recipients, with lengthy periods of intensive care before rejection of the grafts. The substantial lymphoid components in the small intestines are thought to contribute to making the control of immunological reactions that generally occur between graft and host more difficult in small bowel transplant than in other organ transplants. With the use of newer immunosuppressive agents, such as FK 506, transplantation of the small intestine may show improved outcomes as is currently being reported by investigators in Pittsburgh, PA.
- Notes:
- "August 1993."
- Title from title screen (viewed on September 25, 2008).
- Includes bibliographical references.
- Other Format:
- Hotta, S. Steven. Small intestine and combined liver-small intestine transplantation
- OCLC:
- 257511373
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