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Enantiomeric analysis of ephedrines and norephedrines / S.M. Wang [and others].

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Format:
Book
Government document
Contributor:
Wang, S. M.
United States. Office of Aerospace Medicine
Language:
English
Subjects (All):
Ephedrine--Analysis.
Ephedrine.
Phenylpropanolamine--Analysis.
Phenylpropanolamine.
Ephedrine--analysis.
Norepinephrine--analysis.
Designer Drugs--analysis.
Medical Subjects:
Ephedrine--analysis.
Norepinephrine--analysis.
Designer Drugs--analysis.
Physical Description:
1 online resource
Place of Publication:
Washington, DC : Office of Aerospace Medicine ; Ft. Belvior, VA : Available through the Defense Technical Information Center ; Springfield, VA : Available through the National Technical Information Services Office of Aerospace Medicine, [2005]
Summary:
Concerned with variations in abuse potential and control status among various isomers of ephedrines and norephedrines, this study was conducted to develop an effective method for the simultaneous analysis of eight ephedrine-related compounds along with structurally similar cathinones. Among various approaches studied, a 60m HP-5MS (0.25 mm ID, 0.25 micrometer film thickness) was successfully used to characterize the following compounds that were derivatized with ( - )-alpha-methoxy-alpha-trifloromethylphenylacetic acid (MTPA): (+)-cathinone, ( - )-cathinone, (+)-norephedrine, ( - )-norephedrine, (+)-norpseudoephedrine, (+)-ephedrine, ( - )-ephedrine, ( - )-pseudoephedrine, (+)-pseudoephedrine. ( - )-Cathine standard was not available but should also be resolvable under this analytical procedure. This method was successfully applied to the analysis of selected cold remedies for characterizing the enantiomeric compositions of the compounds present in these samples.
Notes:
Title from PDF title page (viewed May 30, 2006).
"April 2005."
"DOT/FAA/AM-05/8."
Includes bibliographical references.
Other Format:
Enantiomeric analysis of ephedrines and norephedrines
Online version: Enantiomeric analysis of ephedrines and norephedrines.
OCLC:
70713396
Access Restriction:
APPROVED FOR PUBLIC RELEASE.

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