In vitro and in vivo models to study infections of the central nervous system edited by Federico Iovino

Format:

Book

Contributor:

Iovino, Federico, 1984- editor.

Series:

Methods in molecular biology (Clifton, N.J.) 1940-6029

Methods in molecular biology 1940-6029

Language:

English

Subjects (All):

Nervous system--Infections.

Nervous system.

Nervous system--Infections--Animal models.

Central nervous system--Diseases.

Physical Description:

1 online resource

Place of Publication:

Springer US 2025

New York, NY Humana Press 2025

Summary:

This groundbreaking volume dives into the devastating impact of infections on the Central Nervous System (CNS), a major culprit behind neurological disorders in both children and adults. From bacteria and viruses to fungi and parasites, a range of pathogens can breach the body's defenses and wreak havoc on the brain. Packed with cutting-edge research, this book unravels the methods and tools used to study how these microbial invaders penetrate human cell barriers, interact with CNS cell types -- especially neurons and microglia -- and contribute to lasting brain damage. As part of the acclaimed Methods in Molecular Biology series, each chapter provides a clear introduction, essential materials and reagents, step-by-step lab protocols, and expert troubleshooting tips to ensure reproducible results. Whether you're a seasoned researcher or just stepping into the field, In Vitro and In Vivo Models to Study Infections of the Central Nervous System is your go-to guide for exploring this critical and rapidly evolving area of study

Contents:

Studying Group B Streptococcus-Blood-Brain Barrier Interaction In Vitro using an Induced Pluripotent Stem Cell Derived Brain-Like Endothelial Cell Model

E Coli. Meningitis

Neuro-Immune Consequences of L. Monocytogenes Infection

In Vitro and In Vivo Models Studying Haemophilus Influenzae

A 3D In Vitro Blood-Brain Barrier Model to Study Pathogen and Drug Effects on the BBB

In Vitro Culture of Primary Mouse Neurons to Study Neuronal Infection

Differentiation of Human Neurons and Neuron-Like Cells to Study VZV Neuronal Infection

Enterovirus Meningitis

Lab Protocols for Coxsackievirus B3 Infection Using Brain-Like Endothelial Cells Derived from Induced-Pluripotent Human Stem Cells

Infection of Macrophages with Cryptococcus neoformans to Evaluate Dissemination to the Central Nervous System

Infection of Mice with Cryptococcus neoformans to Evaluate Dissemination to the Central Nervous System

In Vitro and In Vivo Models of Neuroschistosomiasis

Notes:

Includes index

Online resource; title from PDF title page (SpringerLink, viewed July 17, 2025)

Other Format:

Print version :

ISBN:

9781071646748

1071646745

OCLC:

1528103799

Publisher Number:

CIPO000268178

Access Restriction:

Restricted for use by site license