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Mathematical Modeling of the Healthy and Diseased Lung : Linking Structure, Biomechanics, and Mechanobiology / by Béla Suki, Jason H. T. Bates.

Springer Nature - Springer Biomedical and Life Sciences (R0) eBooks 2025 English International Available online

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Format:
Book
Author/Creator:
Suki, Béla.
Contributor:
Bates, Jason H. T.
Series:
Biomedical and Life Sciences Series
Language:
English
Subjects (All):
Biomedical engineering.
Biomathematics.
Respiratory organs.
Physiology.
Bioinformatics.
Biomedical Engineering and Bioengineering.
Mathematical and Computational Biology.
Respiratory Physiology.
Computational and Systems Biology.
Local Subjects:
Biomedical Engineering and Bioengineering.
Mathematical and Computational Biology.
Respiratory Physiology.
Computational and Systems Biology.
Physical Description:
1 online resource (479 pages)
Edition:
1st ed. 2025.
Place of Publication:
Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Summary:
The lung is a complex multiscale organ that serves as the primary interface between the environment and the tissues of the body. Homeostatic maintenance of lung function throughout life is essential for health. While failure of lung homeostasis underlies many of the most common chronic diseases that afflict mankind, the precise pathophysiologic mechanisms involved are often unclear. Investigative techniques such as microscopic imaging and atomic force microscopy are providing new insights into lung tissue properties at the micro scale. It nevertheless remains to be seen how this growing body of information can be integrated into a comprehensive picture of the lung. Mathematical and computational modeling has emerged as an essential tool for gaining such a holistic understanding. This book introduces the reader to the art of modeling as a means of linking lung structure to function over multiple length scales from the intracellular level to that of the whole organ, with specific attention given to the pathophysiology of a number of common lung diseases and aging.
Contents:
introduction
lung anatomy and physiology
lumped parameter models of lung function
parenchymal tissue elasticity
tissue viscoelasticity
homeostasis and repair
asthma
pulmonary fibrosis
chronic obstructive pulmonary disease
acute lung injury
lung defenses
the aging lung
what is coming next.
Notes:
Description based on publisher supplied metadata and other sources.
Other Format:
Print version: Suki, Béla Mathematical Modeling of the Healthy and Diseased Lung
ISBN:
9783031953224
OCLC:
1527858967

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