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Innate Immunity: Pattern Recognition and Effector Mechanisms / edited by Uday Kishore, Andrew J. T George.

Springer Nature - Springer Biomedical and Life Sciences (R0) eBooks 2025 English International Available online

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Format:
Book
Author/Creator:
Kishore, Uday.
Contributor:
George, Andrew J. T.
Series:
Advances in Experimental Medicine and Biology, 2214-8019 ; 1476
Language:
English
Subjects (All):
Immunology.
Medicine--Research.
Medicine.
Biology--Research.
Biology.
Natural immunity.
Cytology.
Biomedical Research.
Innate Immunity.
Cell Biology.
Local Subjects:
Immunology.
Biomedical Research.
Innate Immunity.
Cell Biology.
Physical Description:
1 online resource (856 pages)
Edition:
2nd ed. 2025.
Place of Publication:
Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Summary:
This contributed volume follows up and expands upon Target Pattern Recognition in Innate Immunity (2009), providing a much-needed update on an area that has surged to the forefront of medical research in recent years. From the initial idea of pattern recognition on microbial surfaces, innate immunity is now recognized as a key player in human health and disease, by virtue of its ability to regulate adaptive immune responses with important physiological and pathological consequences. This book presents cutting edge research and future perspectives on nearly all aspects of innate immunity. Coverage includes cells of the innate immune system, pattern recognition receptors and effector mechanisms, soluble PRRs and humoral factors, immune response to viral, bac-terial, fungal, and parasitic pathogens, disease mechanisms, and comparative studies in non-mammalian innate immunity. It is an excellent introduction to the field for students, and state of the art reference for researchers and professionals.
Contents:
The biology of Dendritic cells-health and disease
Innate lymphoid cells
Primordial cells bridging the gap between innate and adaptive immunity
Pattern recognition by NOD like receptors
The C-type lectin receptors
Collectins and Ficolins
Complement system
Innate immune response to viral infection
Anti-fungal innate immune response
Innate immune response to helminth infection
Trained innate immunity
Interactions between the innate and adaptive immune responses
Role of innate immunity in cancer
Innate immune mechanisms in normal and adverse pregnancy
Innate immune mechanisms in the central nervous system
Invertebrate innate immunity
Pattern recognition and plant immunity.
Notes:
Description based on publisher supplied metadata and other sources.
ISBN:
3-031-85340-7
OCLC:
1527722153

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