Iron in Biology : Molecular Structures, Cellular Processes and Living Systems.

Format:

Book

Author/Creator:

Shiro, Yoshitsugu.

Contributor:

Sawai, Hitomi.

Tosha, Takehiko.

Series:

Coordination Chemistry Perspectives Series

Coordination Chemistry Perspectives Series ; v.Volume 1

Language:

English

Subjects (All):

Iron.

Iron ions.

Physical Description:

1 online resource (372 pages)

Edition:

1st ed.

Place of Publication:

Cambridge : Royal Society of Chemistry, The, 2025.

Summary:

Both an excess and a shortage of iron causes serious diseases. This book focuses on filling the gap in chemical understanding and our real life by providing fundamental information on genetics, drugs and environmental health.

Contents:

Cover

Copyright

Preface

Contents

Section I: Diseases Relating to Cellular Iron Dynamics

Chapter 1 Introduction to Iron Dynamics in Human Cells: Fundamental Mechanisms and Recent Developments

1.1 Iron: A Double-edged Sword Element

1.2 Systemic Iron Homeostasis

1.2.1 Hepcidin: A Main Regulator of Iron Entry Into the Plasma

1.2.2 Erythroferrone (ERFE): An Inhibitor of Hepcidin Synthesis

1.3 Cellular Iron Homeostasis

1.3.1 Cell-type Specific Iron Metabolism

1.3.1.1 Erythroblasts

1.3.1.2 Enterocytes

1.3.1.3 Hepatocytes

1.3.1.4 Macrophages

1.3.2 Intracellular Iron Delivery Mechanism by Iron Chaperones

1.3.3 Roles of Ferritin: Store and Supply Iron in Response to Cellular Requirements

1.4 Summary

Acknowledgments

References

Chapter 2 Dysregulated Iron Dynamics in Cancer

2.1 Introduction

2.2 Iron in Life and Carcinogenesis

2.3 Ferroptosis in Iron Dynamics

2.4 Exosomes in Carcinogenesis

2.5 Conclusion

Abbreviations

References Generated by AI.

Notes:

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

ISBN:

1-83767-798-0

1-83767-797-2

OCLC:

1524422291