Physiology and Pathophysiology of Oligodendroglia / edited by Chenju Yi, Arthur Butt, Alexei Verkhratsky, Jianqin Niu.

Format:

Book

Author/Creator:

Yi, Chenju.

Contributor:

Butt, Arthur.

Verkhratskiĭ, A. N. (Alekseĭ Nestorovich)

Niu, Jianqin.

Series:

Advances in Neurobiology, 2190-5223 ; 43

Language:

English

Subjects (All):

Neurophysiology.

Neurons.

Neurosciences.

Cellular Neuroscience.

Neuroscience.

Local Subjects:

Cellular Neuroscience.

Neuroscience.

Neurophysiology.

Physical Description:

1 online resource (676 pages)

Edition:

1st ed. 2025.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2025.

Summary:

This single volume provides a comprehensive description of oligodendroglia, the neural cells responsible for myelination of axons throughout the central nervous system. Myelinated axons create the white matter (connectome) of the human brain and spinal cord, which connect and synchronize hundreds of billions of neurons, thus defining the information processing function of the central nervous system. Oligodendrocytes and myelination play an essential role in regulating every bodily function and behavior. Damage to white matter, myelin, and oligodendrocytes results in severe diseases of the CNS. Pathology and Pathophysiology of Oligodendroglia, presented by the major authorities in the field, is the very first reference to combine, under a single cover, a full and detailed description of the physiology and pathophysiology of oligodendroglia, with a particular emphasis on neurodegenerative diseases.

Contents:

Preface

Chapter 1: Oligodendroglial lineage, myelin and white matter: defining the connectome of the human brain

Part I: Physiology of oligodendroglia

Chapter 2: Evolution of myelin and oligodendroglia

Chapter 3: Development of oligodendroglia and myelin

Chapter 4: Seeing is believing: insights into myelination and remyelination in zebrafish

Chapter 5: Morphology of oligodendroglial cells and myelin

Chapter 6: Physiology of oligodendroglial cells

Chapter 7: Biochemistry and structure of myelin

Chapter 8: Plasticity of myelination

Part II: Pathophysiology of oligodendroglia

Chapter 9: Demyelination and remyelination: General principles

Chapter 10: Leukomalacia

Chapter 11: White matter injury in the brain and spinal cord

Chapter 12: Multiple sclerosis

Chapter 13: Ageing and neurodegeneration of oligodendroglia

Chapter 14: Protein pathologies in oligodendroglia in neurodegenerative diseases

Chapter 15: Mental disorders

Chapter 16: Neuromyelitis Optica

Epilogue.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-031-87919-8

OCLC:

1523375684