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Metabolomics and Clinical Approach / Sevgi Durna Daştan and Taner Daştan, editors.
- Format:
- Book
- Series:
- Biochemistry and molecular biology in the post genomic era.
- Biochemistry and Molecular Biology in the Post Genomic Era Series
- Language:
- English
- Subjects (All):
- Metabolism.
- Metabolites.
- Physical Description:
- 1 online resource (338 pages)
- Edition:
- First edition.
- Place of Publication:
- New York : Nova Science Publishers, [2023]
- Summary:
- "Metabolomics is the scientific study of chemical processes involving metabolites, substrates, intermediates, and namely all reagents and products of cell metabolism. Metabolomics and Clinical Approach will contribute to the the large-scale scientific study of small molecules within cells, biofluids, tissues or organisms and their interactions within a biological system. Also this book gives a perspective about study steps of metabolomics, the relationship of different diseases and metabolites, and the use of metabolomics in the treatment processes of different clinical pictures and diseases in the light of current information obtained from the literature. This book aims to describe all types of contents, effects, and kinetics of metabolite production related with metabolomics, as well as to summarize from the beginning to the end. Because the significance of metabolomics science and clinical trials increases day by day. Some diseases like cancer are an important cause of mortality for which no definitive treatment has yet been found. Further investigation of the relationship between metabolomics and diseases will open new horizons for diagnosis and treatment of many kind of diseases. This book presents all about metabolomics from the beginning to the end, as many kind of studies, potential mechanisms, diagnosis techniques, the metabolomics technologies like GC-MS, LC-MS, and software programmes about metabolomics analysis"-- Provided by publisher.
- Contents:
- Intro
- Preface
- The Concept of Metabolomics
- Abstract
- Introduction
- Metabolites
- Systems Biology
- The Concepts of Systems Biology and the Omics
- The Omics Technologies
- Genomics
- Transcriptomics
- Proteomics
- Bioinformatics
- Others
- Metabolomics
- Historical Process
- Metabolomics in Different Fields of Study
- Diagnostics and Biomarker Identification
- Cancer Research
- Hereditary Diseases
- Metabolic Pathway Investigations
- Pharmaceutical and Toxicology Research
- Research in Veterinary Medicine
- Food and Nutrition Research
- Agricultural and Crops Research
- Conclusion
- References
- Metabolomics and BMI
- Methods and Aims
- Nucleic acids and BMI
- Proteins and BMI
- Lipids and BMI
- Carbohydrates and BMI
- Metabolites Associated with Age and Aging
- Metabolites Usage in Aging Process
- Geno-Metabolomics:
- Genotype Effects on Metabolites
- From Genomics to Metabolomics
- Pharmaco-Metabolomics: Drug Effects on Metabolites
- Pharmaceutical Metabolomics
- Pharmaco-Metabolomics and Cancer Drugs
- The Dynamic Nature of Metabolism
- The Use of HPLC in Metabolomics Research
- High-Performance Liquid Chromatography
- Components of HPLC Apparatus
- Mobile Phase Chamber
- Degasser
- Pumps
- Autosampler and Injectors
- The Column and Column Heater
- Detector
- Advantages of the HPLC
- The Usage Fields of the HPLC in Metabolomics Research
- Pharmaceutical Applications
- Food Industry Applications
- Environmental Safety Applications
- Industrial Applications
- Biochemical Analyses
- References.
- The Scope of LC-MS-Based Metabolomics
- LC-Based Metabolomics Studies
- MS-Based Metabolomics Studies
- Databases for Metabolomics Research
- Metabolomic Data Mining
- Metabolomic Databases
- The Metabolite Profiling
- Metabolomic Research:
- Past, Present, and Future
- Metabolomics for Biomarker Discovery
- Historical Process of Metabolomic Studies
- Metabolomics Applications Today
- Metabolite Separation Techniques
- Gas Chromatography
- Liquid Chromatography
- Capillary Electrophoresis
- Metabolite Detection Methods
- Mass Spectrometry
- Nuclear Magnetic Resonance Spectroscopy
- Software and Database Support in Metabolomics Studies
- Future Perspective
- Metabolomics in Traumatic Brain Injuries
- The Clinical Impact and Use of Metabolomics in Diabetes Research
- Metabolomics in Diabetes
- Amino Acids
- Lipids
- Carbohydrates
- Nucleotides
- Is The Development of Diabetes Treatment or Prevention Possible with Metabolics Profile?
- The Current State and Future Perspectives of Metabolomics in Orthopedics
- Osteoarthritis
- Osteoporosis
- Rheumatoid Arthritis
- Osteosarcoma
- Biomaterials
- Metabolomics and Metabolic Profiling in Embryos for Viability Assessment
- Analysis Techniques in Metabolomics
- Clinical Practices
- In Vitro Maturation
- Carbohydrate Metabolism
- Amino Acid Turnover
- Metabolomics in the Diagnosis of
- Pregnancy Complications
- Pregnancy and Amniotic Fluid
- Preeclampsia.
- Fetal Growth Restriction
- Preterm Birth
- Metabolomic Markers and Their Clinical Uses in Neurology
- Theoretical Perspectives
- Alzheimer Disease
- Parkinson's Disease
- Huntington Disease
- Motor Neuron Disease
- Cerebrovascular Disease
- Idiopathic Intracranial Hypertension (IIH)
- Multiple Sclerosis
- Epilepsy
- Migraine
- Peripheral Neuropathies
- Metabolomics in Immunology Research
- Relationship of Metabolomics with Immune Diseases
- Methods Used to Determine Metabolomics
- Mass Spectrometry (MS)
- Nuclear Magnetic Resonance (NMR) Spectroscopy
- Metabolomics in Uncovering Biomarkers of Immune Responses
- Investigation of the Effects of Intracellular Signaling Metabolites on Immune Cell Function
- Extracellular Vesicles Untargeted Metabolomics Analysis
- The Clinical Uses of Mass Spectrometry-Based Approaches in Neurology and Psychiatry
- Untargeted Metabolomics
- Targeted Metabolomics
- Mass Spectrometry Approach in Neurology
- Stroke
- Alzheimer's Disease
- Amyotrophic Lateral Sclerosis (ALS)
- Genetic Diseases
- Mass Spectrometry Approach in Psychiatry
- Nutritional Metabolomics and Their Implications in Clinical Studies
- Clinical Studies
- Metabolome in Urology Practices: Signatures in Plasma and Urine
- Important Metabolomics Studies in the Urology Field
- Metabolomic Applications in Food Science and Nutrition
- Metabolomics in Food Science
- Analysis of Food Metabolomics
- Metabolomics in Food Quality.
- Metabolomics in Food Microbiology
- Metabolomics in Food Processing
- Metabolomics for Nutrition
- The Use of Metabolomics in Neonatology
- The Potential of Metabolomics in Pediatrics
- Metabolomics and Asphyxia
- Metabolomics in Intrauterine Growth Retardation (IUGR)
- and Preterm Birth
- Metabolomics and Neonatal Nutrition
- Metabolomics and Sepsis
- Metabolomics and Neuropsychiatry
- Metabolomics and Some Organ Pathologies
- Metabolomics and Inborn Errors of Metabolism
- Metabolomic Profiles of Body Fluids in Preterm Births
- Metabolomics in Predicting Preterm Birth
- Metabolomics in Preterm Morbidities
- The Use of Metabolomics in Diagnosing and Evaluating Inborn Metabolism Errors
- Metabolomics in the Diagnosis of IEM
- Metabolic Screening Tests in Neonates
- Metabolomic Tests Diversity
- Neuropsychiatric Symptoms of IEM
- Metabolomics in Biomarker Identification for Cardiovascular Diseases
- Metabolomics Technologies
- Metabolomics in Cardiovascular Diseases (CVDs)
- Metabolomics in Myocardial Ischemia, Cardiogenic Shock, and Infarction
- Metabolomics in Atherosclerosis
- Metabolomics in Heart Failure
- Index
- Blank Page.
- Notes:
- Description based on print version record.
- Includes bibliographical references and index.
- Other Format:
- Print version: Daştan, Sevgi Durna Metabolomics and Clinical Approach
- ISBN:
- 979-88-911-3181-1
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