Death to beauty : the transformative history of Botox / Eugene M. Helveston.

Format:

Book

Author/Creator:

Helveston, Eugene M., 1934- author.

Language:

English

Subjects (All):

Botulinum toxin--Therapeutic use.

Botulinum toxin.

Surgery, Plastic.

Dermatologic agents.

Physical Description:

1 online resource (216 pages)

Edition:

First edition.

Place of Publication:

Bloomington, Indiana : Indiana University Press Office of Scholarly Publishing, [2024]

System Details:

Mode of access: World Wide Web.

Summary:

"In the 1970s, Dr. Alan Scott sought to selectively weaken eye muscles to treat strabismus (when one or both eyes are misaligned) without surgery. After failed attempts with other agents, Scott developed a method to stabilize the bacteria that causes botulism, culminating in a drug that eventually became known as Botox. In Death to Beauty, Eugene M. Helveston, MD, follows the unlikely story of botulism's 1817 discovery in contaminated German sausages, to its use in military and research facilities, to Scott, an ophthalmologist who aimed to safely use the drug in humans. Scott struggled alone as an unknown in the pharmaceutical industry, searching for clinical trial financing and FDA approval, which he achieved at a fraction of the billions big pharma usually spends to bring a drug to market. Eventually, the company Allergan bought him out, capitalizing on the possibilities for cosmetic uses. Scott's formula was renamed "Botox" and reached annual sales in the billions. After the sale, Scott received no further compensation from Botox sales and remained the same unassuming man.A fascinating walk through the intricate history of how the world's deadliest toxin starting as a treatment for crossed eyes became a routine tool for the cosmetic industry, Death to Beauty will make you rethink success, beauty, and deadly bacteria"-- Provided by publisher.

Contents:

Cover

Title Page

Copyright

Dedication

Contents

Author's Note

Preface

Acknowledgments

1. Clostridium Botulinum

2. The World's Deadliest Poison

3. The Canning Industry

4. An Outbreak in the United States

5. A Rare and Deadly Disease

6. World War II Sets the Stage

7. Camp Detrick-US Army Biological Warfare Laboratories

8. Fort Detrick and the CIA

9. The Government Steps In

10. Edward Schantz Testifies

11. Back in Madison

12. Dr. Alan B. Scott

13. Progress in the Lab

14. First Injection in a Primate

15. First Injection in a Human

16. Joining the Team

17. Manufacturing Begins

18. Marketing and Selling a New Drug

19. Botox and Beauty

20. Dermatology Opens the Floodgates

21. Botox and Neurology

22. The Legacy

Epilogue

Appendices

Glossary

Notes

Index

About the Author.

Notes:

Includes index.

Includes bibliographical references and index.

Description based on print version record.

Other Format:

Print version: Helveston, Eugene M. Death to Beauty

ISBN:

9780253067821

0253067820

9780253067814

0253067812