RNA interference in Agriculture: Basic Science to Applications : From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses / edited by Guy Smagghe, Subba Reddy Palli, Luc Swevers.

Format:

Book

Contributor:

Smagghe, Guy, Editor.

Palli, Subba Reddy, Editor.

Swevers, Luc., Editor.

Series:

Biomedical and Life Sciences Series

Language:

English

Subjects (All):

Life sciences.

Zoology.

Ecology.

Biotechnology.

Life Sciences.

Environmental Sciences.

Local Subjects:

Life Sciences.

Zoology.

Environmental Sciences.

Biotechnology.

Physical Description:

1 online resource (XIX, 715 p. 127 illus., 120 illus. in color.)

Edition:

1st ed. 2025.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2025.

Summary:

The book covers the advanced concepts and creative ideas on the postgenomic tool of RNAi that received the Nobel Prize in 2006. Emphasis was placed on the mechanisms of RNAi, the core machinery and the applications in agriculture. This book covers contributions from academia, industry and Government regulatory authorities. Applications to control major important pest insects, as for example western corn rootworm with use of transgenic plant RNAi. But also attention was given to the use of RNAi as a spray (non-transgenic plant approach) or tree-injection. Examples include the control of Colorado potato beetle and treatment of citrus trees to control Asian citrus psyllid. Additionally, the aspect of biosafety and risk assessment were also covered in the book with input from the bioinformatics and risk assessment testing, combined with regulatory input from EPA-USA and EFSA-EU. In summary, the editors believe that this book provides for the first time an invaluable vast source of basic and applied information for a plethora of scientists in academia, industry, and regulatory, as well as a textbook for graduate and advanced undergraduate students.

Contents:

The road to RNAi-based pest control: A historical perspective

RNA interference: View on its current status since the 2006 Nobel Prize and impact on the agriculture looking to the future

Safety of oligonucleotide-based active ingredients used as crop protection agents

RNA insecticides and biodiversity conservation

Steps toward efficient nanocarrier-mediated gene delivery for RNA interference in insects: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

Symbiont-mediated RNAi: mechanisms, current status and prospects

Message in a vesicle: the role of extracellular vesicle cargo in parasite-host interkingdom communication and spread of systemic RNAi in insects

Plastid-mediated RNA interference for pest control

Sustainable crop protection via reversible acylation of 2’OH groups in dsRNA

RNAi in the red flour beetle (Tribolium castaneum): current status and future perspectives

RNAi in the migratory locust: functional studies of the genes in the formation and development of cuticle

RNAi in Chelicerata, spider and mites: meta-analysis and current status of two model organisms and protocols

The migratory locust as a model for studying the mechanisms of RNAi

si/dsRNAs and miRNAs, mechanisms and interactions

Insect cell lines and RNAi

Resistance to RNAi: mechanisms, current status and prospects

Invention of RNAi biopesticides to psyllid vectors and bacterial pathogens of citrus: Future technologies for gene targeting

RNAi technique and the management of stinkbugs in the Neotropical region of Brazil: From the lens of efficiency and environmental sustainability in integrated pest management (IPM). RNAi technology against forest pests: Opportunities, challenges and future prospects

RNAi in Lepidoptera: current status, impact of enzymatic degradation, and future perspectives

Comparing RNAi and CRISPR in the fall armyworm: a meta-analysis, mechanisms and perspectives

RNAi biopesticides for root-feeding insects

Australian sheep blowfly Lucilia cuprina management: Established methods and RNA interference-based biocontrol

Regulation of RNAi in pesticidal products in the United States

Regulatory landscape surrounding approval and authorisation of dsRNA-based plant protection products in Europe

How to talk about RNA so that people understand it and are comfortable with an unfamiliar technology

CalanthaTM: the first commercialized sprayable dsRNA product for insect control.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-031-81549-1

OCLC:

1523371794