Blood-brain barrier edited by Tatiana Barichello

Format:

Book

Contributor:

Barichello, Tatiana, editor.

Series:

Neuromethods 1940-6045

Language:

English

Subjects (All):

Blood-brain barrier--Laboratory manuals.

Blood-brain barrier.

Physical Description:

1 online resource

Edition:

Second edition

Place of Publication:

Springer US 2025

New York, NY Humana Press 2025

Summary:

This volume details experimental research with applicable models to study physiology, biochemistry, and molecular biology of the blood-brain barrier (BBB). Chapters guide readers through the physiology of BBB, in vitro cell models to study the BBB, in vivo and ex vivo models to evaluate BBB, permeability, influx, efflux transportation, drug delivery through the BBB, invasive and non-invasive imaging techniques to study BBB; and molecular biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and cutting-edge, Blood-Brain Barrier aims to ensure successful results in the further study of this vital field

Contents:

An Overview of the Blood-Brain Barrier

Differentiation of brain mural cells from human pluripotent stem cell-derived neural crest by activation of Notch3 signaling

In vitro 2D and 3D cell models of the human blood-brain barrier: demonstrating the beneficial influence of shear stress on brain microvascular endothelial cell phenotype

Emerging human choroid plexus organoid models for blood–CSF barrier research

Drosophila as a model to study the blood-brain barrier. -Exploring the use of zebrafish in the blood-brain barrier research

Evaluation and quantification of blood-brain barrier permeability in a photothrombotic juvenile rodent stroke model using in-vivo MRI and histology

Transepithelial/transendothelial electrical resistance (TEER) to measure the integrity of blood-brain barrier

Cell penetrating peptide-decorated nanovectors for nose-to-brain delivery - a new treatment option for CNS diseases

Microbial Translocation of the Blood-Brain Barrier

Microdialysis sampling in a free-moving mouse for blood-brain barrier studies

Methods of Delivering Molecules Through the Blood-Brain Barrier for Brain Diagnostics and Therapeutics

Transport across the choroid plexus: How to culture choroid plexus epithelial cells and establish a functional assay system

Increasing BBB Permeability via Focused Ultrasound and Microbubbles: Current Methods in Pre-Clinical Research

Recording leukocyte rolling and adhesion on meningeal vessels by intravital microscopy

Molecular Imaging of Blood-Brain Barrier Permeability in Preclinical Models Using PET and SPECT

Biomarkers for Microvascular Proteins Detection: Blood-Brain Barrier Injury and Damage Measurement (IH, IF, EM, and Quantification of Tight Junction Integrity)

Deep learning and machine learning algorithms: A Blood Brain Barrier Permeability Prediction Model with Accuracy

Notes:

Includes index

Online resource; title from PDF title page (SpringerLink, viewed May 28, 2025)

Other Format:

Print version :

ISBN:

9781071644744

1071644742

OCLC:

1521254661

Publisher Number:

CIPO000215154

Access Restriction:

Restricted for use by site license