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Gene x Environment Interactions: Polygenic Scores and the Impact of an Early Childhood Intervention in Colombia / Orazio Attanasio, Gabriella Conti, Pamela Jervis, Aysu Okbay.
- Format:
- Book
- Author/Creator:
- Attanasio, Orazio.
- Series:
- Working Paper Series (National Bureau of Economic Research) no. w33781.
- NBER working paper series no. w33781
- Language:
- English
- Physical Description:
- 1 online resource: illustrations (black and white);
- Place of Publication:
- Cambridge, Mass. National Bureau of Economic Research 2025.
- Summary:
- We evaluate impacts heterogeneity of an Early Childhood Intervention, with respect to the Educational Attainment Polygenic Score (EA4 PGS) constructed from DNA data based on GWAS weights from a European population. We find that the EA4 PGS is predictive of several measures of child development, mother's IQ and, to some extent, educational attainment. We also show that the impacts of the intervention are significantly greater in children with low PGS, to the point that the intervention eliminates the initial genetic disadvantage. Lastly, we find that children with high PGS attract more parental stimulation; however, the latter increases more strongly in children with low PGS.
- Notes:
- May 2025.
- Print version record
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