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Molecular Male Reproductive Medicine : Biology and Clinical Perspectives / edited by C. Yan Cheng, Fei Sun.

Springer Nature - Springer Biomedical and Life Sciences (R0) eBooks 2025 English International Available online

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Format:
Book
Contributor:
Cheng, C. Yan, Editor.
Sun, Fei, Editor.
Series:
Advances in Experimental Medicine and Biology, 2214-8019 ; 1469
Language:
English
Subjects (All):
Reproduction.
Physiology.
Reproductive health.
Medicine--Research.
Medicine.
Biology--Research.
Biology.
Toxicology.
Endocrine glands.
Endocrinology.
Reproductive Physiology.
Reproductive Medicine.
Biomedical Research.
Endocrine System.
Local Subjects:
Reproductive Physiology.
Reproductive Medicine.
Biomedical Research.
Toxicology.
Endocrine System.
Endocrinology.
Physical Description:
1 online resource (VIII, 442 p. 25 illus., 24 illus. in color.)
Edition:
1st ed. 2025.
Place of Publication:
Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Summary:
This book bridges the gap of basic research in male reproductive biology and its relationship to clinical studies. Bringing together a group of senior investigators with decades of experience in research and clinical investigation and keen interest in collaboration between the two areas, this book provides a balanced treatment of technical and basic research insights and cutting-edge findings, while introducing new ideas for clinical applications of this research. Section I is devoted to clinical aspects including testis biology, prostate biology, and spermatogenesis by senior investigators of male infertility treatment, particularly non-obstructive azoospermia. Section II presents the latest findings in male reproductive biology from a basic research perspective, as well as covering cutting-edge technology such as scRNA-Seq, scATAC-Seq, DNA chromatic accessibility and organization studies, genetic models, cell biology, molecular biology, and biochemistry on testis biology, and spermatogenesis. This book offers not only a cohesive summary of new findings and concepts in basic and clinical male reproductive research, it analyzes and assembles these concepts into a roadmap for the next decade of translational research, bringing lab discoveries to the bedside.
Contents:
Current and Future Applications of Artificial Intelligence to Diagnose and Treat Male Infertility.-Immune Regulation in the Testis and Epididymis
Innate Antiviral Defense of the Male Reproductive System
Basal and Immune Cells of the Epididymis: An Electron Microscopy View of Their Association
Molecular Pathways Implicated in the Differentiation and Function of Epididymal Basal cells
Effect of Endocrine Disruptors on Testicular Function
Unveiling the research void: exploring the reproductive effects of PFAS compounds on male health
Computational Approaches in Spatial Transcriptomics for the Study of Mammalian Spermatogenesis
scRNA-Seq-based transcriptome profiling and relevant bioinformatics approaches to uncover novel insights in studying human spermatogenesis
A Comprehensive Bibliometric Analysis of Orchitis Research from 1980 to 2023
Non-Hormonal Contraception: Current and Emerging Targets
Proteostasis as a Sentry for Sperm Quality and Male Fertility
Sperm DNA Fragmentation and Fertility
The Biology and Regulation of Spermatogonial Stem Cells in the Niche
The interacting Fat1 and Dchs planar cell polarity (PCP) proteins supported by Fjx1 serve as heterodimeric intercellular bridges crucial to support spermatogenesis
Extracellular Vesicles in the Aging Male Reproductive System: Progresses and Perspectives
Intraflagellar transport (IFT) and sperm formation
Microtubule-associated proteins (MAPs) are multi-functional cytoskeletal proteins in the testis that regulate spermatogenesis
Testis is a sanctuary site for HIV-1.
Notes:
Description based on publisher supplied metadata and other sources.
ISBN:
3-031-82990-5
OCLC:
1524422455

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