Regenerative Medicine in Sports and Orthopaedics : A New Approach / edited by Alberto Gobbi, Norimasa Nakamura, John G. Lane, Ignacio Dallo.

Format:

Book

Contributor:

Gobbi, Alberto, Editor.

Nakamura, Norimasa, Editor.

Lane, John G., Editor.

Dallo, Ignacio, Editor.

Series:

Medicine Series

Language:

English

Subjects (All):

Orthopedics.

Sports medicine.

Regenerative medicine.

Stem cells.

Orthopaedics.

Sports Medicine.

Regenerative Medicine and Tissue Engineering.

Stem Cell Biology.

Local Subjects:

Orthopaedics.

Sports Medicine.

Regenerative Medicine and Tissue Engineering.

Stem Cell Biology.

Physical Description:

1 online resource (XX, 486 p. 95 illus., 84 illus. in color.)

Edition:

1st ed. 2025.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2025.

Summary:

This book offers a comprehensive overview of the rapidly evolving field of regenerative medicine, including key breakthroughs in clinical therapies. It is further aimed at facilitating ethical, high-quality research in Sports Medicine and Orthopaedics. Set apart by its unique structure, it bridges the gap between basic science and practical applications. Divided into three distinct sections, it begins by laying a strong foundation, delving into the biological and molecular underpinnings of regenerative medicine, including stem cells, growth factors, gene editing, tissue engineering, nanotechnology, and bio-manufacturing. The second section takes readers on a journey into the clinical applications of regenerative medicine, offering valuable guidance and insights for practitioners. The third section, dedicated to future trends and bio-materials’ applications, sheds new light into the evolving landscape of this field. By providing a structured, comprehensive, and up-to-date resource, it equips researchers, clinicians, residents and students with the knowledge needed to make a positive impact in this ever-expanding domain. Written in collaboration with ISAKOS, this volume serves as an invaluable tool in advancing readers’ understanding and practice in the field.

Contents:

PART 1: OVERVIEW 1. Regenerative Medicine: fact or fiction?

2. Natural healing: can we improve it?

3. MSCs: a new approach

4. Evidence-Based Use of Regenerative medicine

5. Biological therapies in regenerative sports medicine

6. Regulation and regenerative treatments

7. Biological Factors in maintaining joint health

PART 2: BASIC SCIENCE 8. Stem cells: different families

9. Growth Factors in regenerative medicine

10. Multipotent adult progenitor cells

11. Preclinical evidence of MSC-derived exosomes

12. Introduction to the concept of secretome in orthopaedics

13. Micro-RNA in orthopaedics

14. Gene therapy in regenerative medicine

15. Aragonite off-the-Shelf Implant for Articular Cartilage in Early OA

16. Growth and maturation of articular cartilage

PART 3: CLINICAL APPLICATION 17. Advances in meniscal tissue engineering. - 18. Orthobiologics in meniscus pathology

19. Regenerative Medicine in Tendon pathologies

20. New treatments for musculoskeletal diseases

21. New approach with Personalized Platelet Rich Plasma

22. Essential Considerations in Platelet-Rich Plasma Preparations with Emphasis on Platelet Dosing and Bioformulations. There is No One-Size Fits All Method

23. Use of new formulation in Hyaluronic Acid in regenerative medicine

24. Regenerative Medicine to Improve Skeletal Muscle Healing After Injury, Disease, & Aging

25. Early OA treatment using allogeneic human umbilical cord MSCs

26. Meniscus repair using synovial stem cells

27. Regenerative Medicine for Osteoarthritis of the Knee Using Cell Sheets.

28. Adipose-derived cell based products for regenerative medicine

29. Orthobiologically augmented scaffolds in cartilage repair

PART 4: FUTURE TRENDS

30. Biophysical stimulation in regenerative medicine

31. Biological products and biomaterials for tendon regeneration

32. iPS cell-based technology for joint resurfacing

33. Nanotechnologies, bio-materials, and scaffolds.34. Scaffold-free tissue engineering in osteochondral restoration

35. Biomarkers in regenerative medicine and bio-orthopaedics.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-031-84693-1

OCLC:

1524424542