Harnessing the immune system for cancer therapy / Raghav Sundar.

Format:

Video

Author/Creator:

Sundar, Raghav, author.

Language:

English

Subjects (All):

Cancer--Treatment.

Cancer.

Immunological adjuvants.

Physical Description:

1 online resource (1 streaming video file (40 min.))

Place of Publication:

London : Henry Stewart Talks, 2025.

System Details:

video file

Contents:

Introduction

Disclosures

What this talk will cover

What this talk will not cover

Lifetime chance of getting cancer

UK cancer statistics

Paradigm #1

The beginnings of chemotherapy

Advances in genomic biology has improved our understanding of cancer

Understanding cancer pathways

Early 2000s: targeted therapy era

Acquired resistance to targeted therapy

Hallmarks of cancer

Germline mutations vs. somatic mutations

Singapore's Mass Rapid Transport (MRT) map

Bulk RNA sequencing

Single cell RNA sequencing

Spatial profiling

Components of the TME

History of immunotherapy evolution

Steady state of an evolutionary arms race

Checkpoint blockade

Paradigm shift #1

Paradigm #2

Surgery for cancer therapy

Surgery to 'cure' cancer

Adjuvant and neoadjuvant therapy

Total neoadjuvant therapy for rectal cancer

Paradigm shift #2

Paradigm #3

Clinical case 1

Clinical case 2

MMR deficient colon cancer - KEYNOTE 177

1-, 5- and 10-year survival of most common cancers

Paradigm shift #3

Concluding remarks

Thank you.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved August 18, 2025, from https://doi.org/10.69645/JHNS2230.