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Colorectal imaging : from basic to advanced concepts / edited by Luca Saba.

Elsevier ScienceDirect eBook - Biomedical Science 2025 Available online

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Format:
Book
Contributor:
Saba, Luca, editor.
Language:
English
Subjects (All):
Colon (Anatomy)--Radiography.
Colon (Anatomy).
Rectum--Radiography.
Rectum.
Physical Description:
1 online resource (533 pages)
Edition:
First edition.
Place of Publication:
Amsterdam, Netherlands : Elsevier, [2025]
Summary:
Colorectal Imaging: From Basic to Advanced Concepts provides an exhaustive overview of today's basic and advanced principles of colorectal imaging, focusing not only on oncologic but also inflammatory, infective, and ischemic pathologies and complications.
Contents:
Intro
Colorectal Imaging: From Basic to Advanced Concepts
Copyright
Dedication
Contents
Contributors
Preface
Acknowledgments
Section 1: Colorectal cancer basic information
Chapter 1: Colorectal cancer: Biology and pathology
Introduction
Dysplasia of the colorectal mucosa
Adenomas
Familial adenomatous polyposis
Peutz-Jeghers syndrome
MUTYH-associated polyposis
Lynch syndrome
Histological report and staging
Molecular pathology of CRC
MSI testing
KRAS testing
BRAF testing
Artificial intelligence and CRC
Conclusions
References
Chapter 2: Principles of surgical treatment
Presurgical phase
Clinical assessment
Anoscopy
Colonoscopy
Surgical preparation
Multidisciplinary team
Prophylaxis
General principles of colorectal surgery
Techniques
Ileocolic resection
Right hemicolectomy
Transverse colon, left colonic flexure resection
Anterior rectal resection
Hartmann's resection
Abdominal resection (Miles's procedure)
Total colectomy
Surgical strategies
Specific considerations on restoration of bowel continuity
Type of anastomosis
Intestinal stomas
Surgical principles for colorectal benign disease
Inflammatory bowel diseases
Epidemiology
Etiology
Complications of IBD
Ulcerative colitis
Crohn's disease
Diverticular disease
Indication for surgery
Uncomplicated acute diverticulitis in an immunocompetent patient
Acute diverticulitis with CT findings of pericolic gas
Acute diverticulitis with abscess
Acute diverticulitis with CT findings of distant gas
Diverticular perforation and diffuse peritonitis
Colorectal cancer
Surgical oncologic principles
Surgical management of colon cancer
Cancerized polyps.
Pathological features and risk assessment
Clinical and patient-specific considerations
Endoscopic excision techniques
Locally advanced colon cancer (stage I-III)
Surgical management of rectal cancer
Stage I
Transanal endoscopic operations: TEM, TEO, TAMIS
Surgical resection
Stage II-III resectable (cT3-4 e/o N1-2)
Nonoperative management for rectal cancer after neoadjuvant therapy
Stage II-III unresectable
Chapter 3: Systemic therapies for localized colon cancer and metastatic colorectal cancer
Principles of treatment
Types of systemic therapy
Cytotoxic chemotherapy
Fluoropyrimidines
Oxaliplatin
Irinotecan
Therapies targeting the epidermal growth factor receptor
Therapies targeting BRAF
Therapies targeting angiogenesis
Immunotherapy
Current treatment pathways
Localized colon cancer
Adjuvant chemotherapy
Neoadjuvant chemotherapy
Metastatic colorectal cancer
Resectable disease
Unresectable disease
First-line therapy
Second-line therapy
Third-line therapy
Future developments
Adaptation of existing therapies
Novel therapies
Embracing new technologies
Chapter 4: Radiotherapy: The role of imaging in the management of rectal cancer
Early
Locally advanced
Advanced
Role of imaging in staging
Tumor location
Tumoral staging: cT
Nodal staging: cN
PET-TC role
High-risk factors
Tumor deposits
EMVI
Mucinous tumor
Target volume definition and delineation
MRI in response assessment in rectal cancer after neoadjuvant treatments
Posttreatment changes in tumor signal
Role of MRI in evaluating lymph nodes posttreatment
Defining complete clinical response
Follow-up
Follow-up on watch-and-wait strategy and organ preservation.
Future perspectives: The use of radiomic parameters in rectal cancer response assessment
Section 2: Colorectal cancer imaging
Chapter 5: CT imaging of colon cancer
Diagnostic and screening principles
CT imaging
Computed tomography colonography (CTC)
Indications
Contraindications
Colon preparation
Bowel cleansing
Diet
Cathartic agents
Residual fluid/solid fecal tagging: Oral contrast
Minimal preparation CT (MPCT) techniques
Colon distention
Balloon catheter
Gas insufflation technique
Spasmolytics
Complications: Perforation
CTC scanning technique
Parameters
Intravenous contrast (IVC) and CTC protocols
Decubitus
Distention grade evaluation
2D and 3D image interpretation and reporting
Features of colonic polyps at CTC
Size
Features of colonic masses at CTC
Classification of colonic lesions: C-RADS
Pitfalls and differential diagnoses
Mimicking polyps
Polyps vs stools
Sticky solid colonic residue
Colonic diverticula
Gas bubbles
Ileocecal valve
Lipoma
Mimicking stenotic mass
Transient colonic spasm
Diverticular disease stricture
Particular case: flat polyps
Standard CT
Staging CT protocol
Preparation
Scanning technique
Reporting: Colon cancer CT Features
Morphology and composition
Clinical TNM staging
Locoregional staging
T staging
Imaging T morphological criteria: limitations and challenges
T1-T2: limited to the bowel wall
T3: Invasion into the pericolic fat
T4: Invading serosa and beyond
T staging accuracy
Extramural vascular invasion (EMVI)
N staging
Suspicious nodes (N+): Criteria and accuracy
Location
Distant staging: M evaluation
CT Follow-up role
Liver metastases
Typical appearance of colorectal cancer liver metastasis.
Accuracy of imaging
Lung metastases
Typical appearance of colorectal cancer lung metastases
Peritoneal metastases
Imaging features of peritoneal carcinosis on CT
Colon cancer complications: Diagnosis in emergency setting
Colonic obstruction
Imaging findings
Intussusception
Colonic perforation
Conclusion and new prospectives
Chapter 6: CT imaging of rectal cancer
Rectum anatomy
Pathophysiology
Symptoms
Risk factors and correlated diseases
Familial adenomatous polyposis syndrome
The role of CT
Basics of rectal tumor appearance on CT
History
MRI comparison
Where does CT scan fit in?
Exam protocol
CT staging
N-staging
M-staging
Imaging of metastatic disease
Hematogenous spread
Lymph node spread
The importance of CT in follow-up
CT colonography
Protocol
Rectal colonography evaluation
Rectal polyps in CT colonoscopy
Local complications
Recurrent disease
New frontiers
PET-CT
Dual-energy CT
Radiomics
Photon counting computed tomography
Chapter 7: US Imaging of rectal cancer
Technique of examination
Interpretation of ERUS findings
Other features
Evaluation of response to neoadjuvant therapy
Special techniques
Chapter 8: MR imaging of rectal cancer
Conducting high-quality MR examinations
Anatomy of the rectum and surrounding structures
Boundaries of the rectum
Rectal wall
Anal canal and pelvic floor
Mesorectal fascia
Peritoneum and peritoneal reflection
Extramesorectal organs and structures
Vascular supply
Lymph nodes
Morphological characteristics of rectal tumors
Tumor height and length.
Polypoid vs sessile tumors
Solid vs mucinous tumors
Local invasion and T-staging
Mesorectal fascia involvement
Lymph node assessment
Regional lymph nodes: Mesorectal lymph nodes
Regional lymph nodes: Lateral lymph nodes
Non-regional lymph nodes
Risk stratification
Future directions
Conclusion
Chapter 9: Posttreatment imaging of colorectal cancer
Colon cancer
Imaging after chemotherapy
Neoadjuvant therapy
Adjuvant therapy
Imaging after surgery
Types of surgery
Normal postoperative findings
Postoperative complications
Imaging of recurrence
Rectal cancer
Response evaluation after neoadjuvant treatment
MRI protocol
Evaluation of tumor response
T2 imaging
Diffusion-weighted imaging
Evaluation of lymph nodes
Evaluation of regrowth and recurrence
Regrowth during watch-and-wait
Luminal regrowth
Nodal regrowth
Recurrence after resection
Chapter 10: Lymph node imaging in colorectal cancer
Lymph node groups relevant to the colon and rectum
Lymph node imaging in colon cancer
The need for preoperative risk stratification
The role of CT in predicting positive lymph nodes
Lymph node size/diameter
Internal heterogeneity
Lymph node clustering
Irregularity of the outer border
Lymph node shape
The role of CT in predicting clinical outcomes
Pathways of colorectal cancer spread
CT extramural venous invasion
Extranodal tumor deposits
The CT-TDV staging system
MRI and local staging of colon cancer
Mismatch repair status and local staging of colon cancer.
Lymph node imaging in rectal cancer.
Notes:
Includes bibliographical references and index.
Description based on publisher supplied metadata and other sources.
Description based on print version record.
ISBN:
9780443290497
0443290490
OCLC:
1500763876

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