Low-intensity control of nerve tissue activity / Mikhail N. Shneider, Mikhail Pekker.

Format:

Book

Author/Creator:

Shneider, Mikhail N., author.

Pekker, Mikhail, author.

Contributor:

Institute of Physics (Great Britain), publisher.

Series:

IOP (Series). Release 24.

IPEM-IOP series in physics and engineering in medicine and biology

IOP ebooks. 2024 collection.

[IOP release $release]

IOP ebooks. [2024 collection]

Language:

English

Subjects (All):

Epithelial cells--Electric properties.

Neural stimulation.

Electric stimulation.

Epithelial Cells--physiology.

Electric Stimulation--methods.

Electric Stimulation.

Medical Subjects:

Epithelial Cells--physiology.

Electric Stimulation--methods.

Electric Stimulation.

Local Subjects:

Epithelial cells--Electric properties.

Neural stimulation.

Electric stimulation.

Physical Description:

1 online resource (various pagings) : illustrations (some color).

Place of Publication:

Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2024]

System Details:

Mode of access: World Wide Web.

System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.

Biography/History:

Dr. Mikhail N Shneider has a PhD in Plasma Physics and Chemistry from the All-Union Electrotechnical Institute in Moscow, and he also has a Doctor of Sciences degree in Plasma Physics and Chemistry from the Institute for High Temperatures, Russian Academy of Sciences, Moscow. Since 1998 up until the present time, Dr. Shneider has been working as a Senior Research Scholar within the Department of Mechanical and Aerospace Engineering, Princeton University. His research interests are in the theoretical study of discharge physics, gas and hydrodynamics, non-linear optics, and biophysics. He has published about 250 papers and 2 books. Dr. Mikhail Pekker has a PhD in physics and mathematics from the Institute of Theoretical and Applied Mechanics in Russia. From 1993-2007, he worked in the Institute of Fusion Studies at the University of Texas, Austin, from 2010 - 2014 at Drexel University and 2015 - 2017 in the Department of Mechanical and Aerospace Engineering at George Washington University. At present he is retired, but still conducts research in gas discharge physics, cavitation, cosmology, and biophysics. Dr. Pekker has more than 100 publications and 1 book.

Summary:

Our book is written primarily for biologists and physicians but also for physicists, engineers, and students who want to understand the mechanisms of stimulation and signal propagation in nervous tissue. It describes in detail the mechanism of ephaptic coupling, which involves the transmission of excitation from an active neuron to a nearby inactive neuron through a conducting intercellular medium. This connection plays an important role in the functioning of the nervous system.The book explains how the interaction of the axon membrane with the electric field of low-intensity microwave radiation leads to a redistribution of transmembrane ion channels in the region of the initial segment of the axon, resulting in an increase or decrease in the threshold for action potential excitation, depending on the radiation intensity. IPEM-IOP Series in Physics and Engineering in Medicine and Biology. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.

Contents:

1. Historical review

1.1 'Living' electricity

1.2. Nernst potential and Bernstein hypothesis

1.3. Squid giant axon

1.4. Model of squid axon proposed by Hodgkin and Huxley

1.5. Ion channels and pumps

1.6. Myelinated nerve fibers, ephaptic coupling

1.7. Synapses

1.8. Optogenetics and thermogenetics

1.9. Green fluorescent protein (GFP) diagnostics

2. Ephaptic coupling and related phenomena

2.1. Estimates of myelin segment length and action potential propagation velocity

2.2. Key experiments in ephaptic coupling

2.3. Ephaptic coupling. A physical-mathematical model

2.4. Physical model of electrical synapses in a neural network

3. On the criteria of nonthermal interaction of cell membranes exposed to microwave radiation

3.1. Phase transition in cell membranes during heating

3.2. Influence of anesthetic drugs and pH on membrane phase transitions

3.3. Conclusions

4. Nonthermal weak microwave field impact on nerve fiber activity

4.1. Brief introductory overview

4.2. Effect of low-intensity microwave radiation on the neuron : qualitative picture

4.3. Lateral diffusion and drift of transmembrane proteins in an acoustic field

4.4. Redistribution of transmembrane channels in a standing acoustic wave

4.5. Ultrasound absorption during ion channel redistribution

4.6. Microwave radiation in water and weak electrolytes

4.7. Forced vibrations of the membrane in a microwave field

4.8. Model of membrane vibrations in the electromagnetic field of microwave radiation

4.9. Elastic cylindrical membrane

4.10. Electromagnetic pollution of the human environment

4.11. Discussion

4.12. Conclusions

5. Interaction between electrolyte ions and the surface of a cell lipid membrane

5.1. Introduction

5.2. An electrostatic model of the phospholipid membrane. Potential distribution near the membrane surface

5.3. Phenomenological theory of surface charge (Stern layer) on the phospholipid membrane

5.4. Discussion

5.5. Conclusions

6. Bypassing damaged areas in neural tissues

6.1. Introduction

6.2. Bypassing a damaged area of nerve tissue by transmitting an action potential

6.3. Discussion of the possibility of bypassing with noncontact electrodes

6.4. Additional notes

7. Theoretical model of external spinal cord stimulation

7.1. Introduction

7.2. Examples of electrical stimulation experiments on the spinal cord nerve

7.3. Computational models for epidural electrical stimulation of spinal nerves

7.4. Results and discussion

7.5. Concluding remarks

8. Anesthesia stimulated by a train of electrical pulses

8.1. Introduction

8.2. Theoretical model

8.3. Potential and current distribution inside the outer dielectric cylinder

8.4. Discussion

8.5. Conclusions

9. Effects of osmotic pressure variations on cell membranes

9.1. Introduction to osmosis

9.2. Experiments on cells in physiological solution interacting with plasma

9.3. Ions introduced by a plasma source at the interface and their deep diffusion into solution

9.4. Estimation of cell size variation with changing ion concentration in solution

9.5. Estimation of the osmotic pressure drop across the cell membrane

9.6. Selective effect of nonequilibrium low-temperature plasma interacting with healthy and cancerous cells in a Petri dish

9.7. Water flux across the lipid membrane induced by the change in osmotic pressure difference

9.8. The dielectric constants of cell membranes and the excitation thresholds of the action potential

9.9. Changing the speed of action potential propagation

9.10. Concluding remarks.

Notes:

"Version: 20241201"--Title page verso.

Includes bibliographical references.

Title from PDF title page (viewed on January 17, 2025).

Other Format:

Print version:

ISBN:

9780750360340

9780750360333

OCLC:

1485258703

Access Restriction:

Restricted for use by site license.