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PI3K/AKT/mTOR Signaling Network in Human Health and Diseases
- Format:
- Book
- Author/Creator:
- Chamcheu, Jean Christopher, Editor.
- Language:
- English
- Physical Description:
- 1 online resource
- Place of Publication:
- Basel MDPI - Multidisciplinary Digital Publishing Institute 2025
- Language Note:
- English
- Summary:
- In recent years, researchers have shown a special interest in the role of signaling pathways as disease molecular targets and capitalized on such pathways to derive natural products, biologics, and synthetic scaffold-based prevention and treatments. These can lead to naturally available, efficacious, low-cost, and minimally toxic long-term therapies for human diseases. This Special Issue of Cells comprises an array of literature reviews, original communications, and studies on the roles of the PI3K/AKT/mTOR and associated pathways in a diversity of pathways using in vitro cell-based assays and preclinical animal models. The authors of the papers also explore technologies designed to improve the bioavailability and delivery of certain compounds. In lieu of ongoing research on a variety of human disorders, the wealth of information published in this Special Issue can act as a springboard for the identification of novel disease targets and the development of new preventive and therapeutic modalities for the management of human diseases.
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