WHO Recommendations for Management of Serious Bacterial Infections in Infants Aged 0-59 Days.

Format:

Book

Author/Creator:

World Health Organization, author, issuing body.

Language:

English

Subjects (All):

Neonatal intensive care.

Newborn infants--Diseases.

Newborn infants.

Physical Description:

1 online resource (0 pages)

Edition:

1st ed.

Place of Publication:

Geneva : World Health Organization, 2025.

Summary:

The World Health Organization (WHO) has developed guidelines for the management of infants aged 0-59 days with serious bacterial infections (sepsis, meningitis, and pneumonia) in hospital and also outside hospital if referral is not possible. The guidelines now include recommendations on diagnosis as well as first line empiric antibiotic treatment of the most critically ill infants aged 0-59 days with suspected sepsis, meningitis and pneumonia. The recommendations are intended for a wide audience involved in the management of serious bacterial infections in infants aged 0-59 days.

Contents:

Intro

_1.1_Background

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Acknowledgements

Abbreviations

Executive summary

1. Introduction

1.1 Background

1.2 Target audience

1.3 Scope of the guideline

2. Methods

2.1 Contributors to the guideline

2.2 Declaration of interests by external contributors

2.3. Identifying priority questions and outcomes

2.4 Evidence search, retrieval and review

2.5 Grading of the quality and certainty of the evidence

2.6 Review of evidence, decision-making and recommendations

2.7 Document preparation and peer review

2.8 Presentation of the recommendations and evidence

3. Recommendations and evidence

A. Non-hospital settings

A.1 Diagnostic accuracy of clinical signs of sepsis in young infants aged 0-59 days in non-hospital settings

A.2 Critical illness in young infants aged 0-59 days in non-hospital settings

A.3 Clinical severe infection in young infants aged 0-59 days in non-hospital settings

A.4 Isolated fast breathing in young infants aged 0-6 days in non-hospital settings

A.5 Isolated fast breathing in young infants aged 7-59 days in non-hospital settings

B. Hospital settings.

B.1 Diagnostic accuracy of clinical signs of sepsis in young infants aged 0-59 days in hospital settings

B.2 Suspected sepsis in young infants aged 0-59 days in hospital settings

B.3 Suspected staphylococcal sepsis in young infants aged 0-59 days in hospital settings

B.4 Suspected meningitis in young infants aged 0-59 days in hospital settings

B.5 Suspected pneumonia in young infants aged 0-59 days in hospital settings

B.6 Suspected staphylococcal pneumonia in young infants aged 0-59 days in hospital settings

C. Cross-cutting issues

4. Implementation

5. Applicability issues

6. Research implications

7. Dissemination

8. Monitoring and evaluating the impact of the recommendations

9. Updating of the guideline

References

Annex 1. Contributors to the guideline

Annex 2. Summary of declarations of interest from the Guideline Development Group (GDG) members and how they were managed

Annex 3. Research priorities

Annex 4. Summary of key details for each priority question and recommendation.

Notes:

Description based on publisher supplied metadata and other sources.

Includes bibliographical references.

OCLC:

1507696482