Discovery of oncogenes / Robert A. Weinberg.

Format:

Video

Author/Creator:

Weinberg, Robert A., author.

Language:

English

Subjects (All):

Pathology, Molecular.

Cancer cells.

Physical Description:

1 streaming video file (42 min., 34 sec.) : color, sound

Place of Publication:

London : Henry Stewart Talks Ltd, 2025.

System Details:

video file

Contents:

Introduction

Tumors arise from specific cells of origin (1)

Tumors arise from specific cells of origin (2)

Cancer can be induced?

Chemical agents can induce cancer

Lung cancer risk in heavy smokers vs. nonsmokers

Impact of environment on cancer incidence

Discovery of chicken sarcoma virus

Electron micrograph of a cell infected by retrovirus

Monolayer cultures exposed to oncogenic stimulus

Transformed cells forming foci

Properties of transformed cells

Chromosomal aberrations and genetic alterations

The Ames test

Mutagenic vs. carcinogenic potency

The life cycle of RSV

Capture of src by Avian Leukosis Virus (ALV)

Structure of ALV and RSV

Evolutionary tree of the c-src proto-oncogene

Retroviral oncogenes in acute transformation

Transfection of DNA of transformed cells

Foci of transformed cells

Homology between transfected and retroviral oncogenes

Altered retrovirus-associated oncogenes in human cancers

Role of HER2/neu in breast cancer progression and survival

Impact of N-MYC amplification on neuroblastoma

Cloning of transfected human oncogenes

A subtle change in a gene of 6,000 bases

The structure of the Ras proteins

The Ras signaling cycle

Map of growth-stimulatory signaling circuit within cells

What we've learned over the past 40 years

Thank you.

Notes:

Description based on publisher supplied metadata and other sources.

Retrieved August 14, 2025, from https://doi.org/10.69645/EWAN1397.