Doctored : fraud, arrogance, and tragedy in the quest to cure Alzheimer's / Charles Piller.

Format:

Book

Author/Creator:

Piller, Charles, author.

Language:

English

Subjects (All):

Alzheimer's disease--Research--Corrupt practices--United States.

Alzheimer's disease.

Physical Description:

xi, 338 pages : illustrations ; 24 cm

Edition:

First One Signal Publishers/Atria Books hardcover edition.

Other Title:

Fraud, arrogance, and tragedy in the quest to cure Alzheimer's

Place of Publication:

New York : One Signal Publishers, Atria, 2025.

Summary:

"For readers of Empire of Pain and Dopesick, an arresting deep dive into how Alzheimer's disease treatment has been set back by corrupt researchers, negligent regulators, and the profit motives of Big Pharma. Nearly seven million Americans live with Alzheimer's disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller's Doctored shows that we've quite likely been walking the wrong path to finding a cure all along--led astray by a cabal of self-interested researchers, government accomplices, and corporate greed. Piller begins with a whistleblower--Vanderbilt professor Matthew Schrag--whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize-rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Piller's revelations of Schrag's findings stunned the field and the public. From there, based on years of investigative reporting, Doctored exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimer's research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field's institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimer's disease, but for scientific research, funding, and oversight at large"-- Provided by publisher.

Contents:

A vanishing mind

"Magic hands"

"Everything is figureoutable"

The French connection

Prodigy meets genius

One hundred years of solitude

Drug of choice

Image problem

Doctored

"Biology doesn't care"

Trust but verify

The "amyloid mafia"

Blots on a field

Federal failures

Scholarly deceptions

Ivory tower deceits

Shock and duty

Slow-motion meltdown

Survival mode

Brain games

Impact on Alzheimer's

Innovation and hope.

Notes:

Includes bibliographical references and index.

Other Format:

Online version: Piller, Charles. Doctored

ISBN:

9781668031247

1668031248

9781668031254

1668031256

OCLC:

1438665736

Publisher Number:

90101067753