Imaging and Focal Therapy of Early Prostate Cancer / edited by Thomas J. Polascik, Jean de la Rosette, Rafael Sanchez-Salas, Ardeshir R. Rastinehad.

Format:

Book

Author/Creator:

Polascik, Thomas J.

Contributor:

de la Rosette, Jean.

Sanchez-Salas, Rafael.

Rastinehad, Ardeshir R.

Mottaghi, Mahdi.

Series:

Medicine Series

Language:

English

Subjects (All):

Urology.

Oncology.

Radiology.

Local Subjects:

Urology.

Oncology.

Radiology.

Physical Description:

1 online resource (497 pages)

Edition:

3rd ed. 2024.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2024.

Summary:

This book encompasses an up-to-date, comprehensive review of the state-of-the-art for prostate gland preserving therapies. It provides insight into the latest research and clinical applications of image-guided diagnosis and minimally invasive focal, gland-preserving treatment for prostate cancer. Fully updated and revised, this text evaluates the scientific evidence for the evolving trend to treat intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, image-targeted therapy methods. Imaging and Focal Therapy of Early Prostate Cancer, Third Edition opens with a discussion of why patients and clinicians should consider focal therapy, then moves on to consider the question of active surveillance versus focal therapy from a global perspective, with chapters on North American, European, Southeast Asian, and South American perspectives. From there, chapters cover the scientific foundation of focal therapy, current and new approaches to image cancer foci within the prostate (multiparametric ultrasonography, multiparametric magnetic resonance imaging, etc.) and various biopsy techniques. Following this is detailed coverage of patient selection, treatment strategy, adjuvants to enhance therapy, outcomes, and patient centered interests, followed by a discussion of the strengths and limitations of various therapeutic modalities, such as cryotherapy, high intensity focused ultrasound, and photodynamic therapy, follows. The final sections of the book cover the assessment of focal therapy outcomes and look forward to the future of focal therapy for prostate cancer. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, this text is designed as a comprehensive resource for urologists, radiation oncologists, medical oncologists, radiologists, uropathologists, molecular biologists, biomedical engineers, residents, fellows, nurses and allied professionals, and researchers with an interest in the diagnosis and novel targeted treatment of prostate cancer.

Contents:

Part I. Why Consider Focal Therapy?

1. What is Focal Therapy for Prostate Cancer? A Guide for Patients

2. Evolution of Focal Therapy for Localized Breast Cancer: Lumpectomy

3. Image-targeted Therapy for Localized Kidney Cancer

4. The Patient’s Perspective: What Does the Patient Want?

Part II. Global Perspective of Active Surveillance (AS) and Focal Therapy (FT)

5. Intersection of AS and Radical Therapy: Opportunities for FT in North America.

6. FT and AS of Prostate Cancer - A European Perspective

7. FT and AS of Prostate Cancer in Southeast Asia and the East

8. FT Perception and Acceptance in South America

Part III. The Focal Therapy Concept: Scientific Foundation

9. Understanding Tumor Biology and Pathology - Cancer Grade, Volume, and Spatial Location – as a Foundation for Focal Therapy

10. Identifying and Characterizing the Index Lesion

11. The Role of Molecular Techniques to Distinguish Low Grade from Lethal Cancers

12. Utilizing Biopsy-based Genomic Assays to Risk Stratify Patients for Active Treatment

13. Can Understanding and Utilizing the Tumor Microenvironment Enhance the Therapeutic Efficacy of FT?

14. Differences between MRI Visible vs Invisible Cancers: Biology and Outcomes

Part IV. Prostate Imaging and Staging

15. PIRADS Reporting Standards and Limitations for Cancer Detection in the Peripheral Zone vs Transition Zone, PI-QUAL, and Standardization in MR Quality

16. Employing a Quality Improvement Program to Optimize mpMRI-directed Fusion Biopsy

17. Multiparametric Ultrasound for Prostate Imaging and Targeting

18. What is Necessary for FT Staging: Cross-sectional vs PET vs Nil?

Part V. Image-Targeted Prostate Biopsy Techniques

19. mpMRI-TRUS Prostate Fusion Biopsy Commercial Systems.-20. Comparison of Outcomes with Transperineal vs Transrectal Image-targeted Prostate Biopsy

21. Using Multicore, Transperineal Prostate Mapping Biopsy to Detect, Localize and Treat the mpMRI Invisible Lesion

22. Multi-parametric Ultrasound (mpUS) Biopsy

23. Diagnostic Performance of PET-based Targeted Fusion Biopsy in Prostate Cancer

24. Optimizing biopsy core quality for diagnosis

Part VI. Patient Selection and Ablation Treatment Schema

25. Patient Selection: What Tumors Should Be Treated Based on Grade, Size, Location, Genetics and Risk Category?

26. Definitions and Common Terminology for Focal Prostate Ablation

27. Focal Therapy for Anterior Cancers

28. Office-based Outpatient Focal Therapy

Part VII. Transperineal Technologies for Focal Therapy

29. Focal Brachytherapy and IMRT

30. In-bore Transperineal MRI-Guided Laser Ablation

31. Focal Cryoablation

32. Irreversible Electroporation for Partial Gland Ablation: Clinical Application and Outcomes

33. Photodynamic Therapy

Part VIII. Transurethral Technologies for Focal Therapy

34. Role of TULSA as a Focal Therapy in Prostate Cancer

35. Transurethral Vapor Ablation in Prostate Cancer

Part IX. Transrectal Technologies for Focal Therapy

36. Robotic High-Intensity Focused Ultrasound

37. Transrectal laser ablation of prostate cancer

Part X. Post-treatment Assessment of Focal Therapy Outcomes

38. Role of Prostate MRI for Post-treatment Assessment and Surveillance

39. Measuring patient-based outcomes: setting realistic expectations when balancing functional outcomes with cancer control

40. Assessing Functional Outcomes after Focal Therapy

41. Biochemical Assessment of Cancer Outcomes following Focal Therapy

42. Pathologic Assessment and Implications following Prostate Focal Therapy

43. Salvage Options after Focal Therapy Recurrence

Part XI. Looking forward

44. Design of Payment and Reimbursement Strategies for Focal Therapy for Acceptance in Value Based Care Models

45. The Horizon: Future of Focal Therapy in Prostate Cancer.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

9783031667541

3031667549

OCLC:

1478702534