Human and Animal Relationships / edited by Axel A. Brakhage, Olaf Kniemeyer, Peter F. Zipfel.

Format:

Book

Author/Creator:

Brakhage, Axel A.

Contributor:

Kniemeyer, Olaf.

Zipfel, Peter F.

Series:

The Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research, 2945-8056 ; 6

Language:

English

Subjects (All):

Fungi.

Mycology.

Microbiology.

Medical microbiology.

Physiology.

Cytology.

Immunology.

Medical Microbiology.

Animal Physiology.

Cell Biology.

Local Subjects:

Fungi.

Medical Microbiology.

Animal Physiology.

Cell Biology.

Immunology.

Physical Description:

1 online resource (283 pages)

Edition:

3rd ed. 2024.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2024.

Summary:

Estimates based on sequencing data suggest that there are around 5.1 million species of fungi. Yet only a small number of fungi are harmful to animals, including humans. In addition to host-pathogen interactions, there are also mutualistic interactions between fungi and animals. Diseases caused by pathogenic fungi range from allergic reactions and superficial infections to invasive mycoses, and have a significant impact on human and animal life. Fungi are also cultivated by animals as a food source in highly developed relationships or are even involved in gut mutualism. This 3rd edition of Volume 6 of The Mycota highlights exemplary interactions between fungal pathogens and their host(s). The book is organized in three parts: Part 1 summarizes our current understanding of important pathogenic fungi such as Candida species, Malassezia yeasts, Aspergillus fumigatus and fungi of the order Mucorales. Part 2 addresses the characterization of the host response towards pathogenic fungi. It focuses on RNA as a mediator of host-pathogen interactions, the human gut mycobiome, the role of the innate immune system in fighting infections, pattern recognition receptors involved in fungal infections, and a summary of established infection models for studying host-fungal-pathogen interactions. Part 3 provides insights into the impact transcriptomics and proteomics technologies have on the research of human-pathogenic fungi. The up-to-date reviews by experts in the field provide the reader with a comprehensive overview of the various research topics in the field of human and animal relationships with fungi and will hopefully help researchers to find inspiration for their own research.

Contents:

Part I. Pathogens

Chapter 1. Trinity of Environment, Animals, and Humans: A Résumé in the Case of the Fungal Order Mucorales

Chapter 2. Pathogenicity Strategies of Candida Species During Interaction with Epithelial Cells

Chapter 3. Malassezia Yeasts in Animals in the Next-Generation Sequencing Era

Chapter 4. Extracellular Proteins and Their Roles in Aspergillus Fumigatus Pathogenesis

Part II. Host-Pathogen Interaction

Chapter 5. RNA as a Mediator of Host-Fungal Pathogenesis

Chapter 6. The Human Gut Mycobiome and Its Potential as a Regulator of the Host’s Metabolic Health

Chapter 7. The Host Innate Immune Response to Pathogenic Candida Albicans and Other Fungal Pathogens

Chapter 8. Mammalian Pattern Recognition Receptors (Prrs) Involved in Recognition of Fungi

Chapter 9. Infection Models for Human Pathogenic Fungi

Part III. Techniques

Chapter 10. Transcriptomic Analyses of Host Colonisation in Fungal Pathogens of Humans

Chapter 11. Proteomics and Its Application to the Human-Pathogenic Fungus Aspergillus Fumigatus.

ISBN:

9783031648533

3031648536