Proteogenomics : Methods and Protocols / edited by Jens Allmer, Abhishek Kumar.

Format:

Book

Contributor:

Allmer, Jens, Editor.

Kumar, Abhishek, Editor.

Series:

Methods in Molecular Biology, 1940-6029 ; 2859

Language:

English

Subjects (All):

Bioinformatics.

Local Subjects:

Bioinformatics.

Physical Description:

1 online resource (XIII, 334 p. 53 illus., 48 illus. in color.)

Edition:

1st ed. 2025.

Place of Publication:

New York, NY : Springer US : Imprint: Humana, 2025.

Summary:

This volume presents an up-to-date overview of the current state-of-the-art protocols, and aims to put proteogenomics into a broader perspective. The chapters in this book detail methods and techniques ranging from mass spectrometry to proteomics and proteogenomics and their biomedical implications and applications. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. A highlight for everyone new to the field are the chapters, which put proteogenomics to use to answer biomedical questions. Authoritative and accessible, Proteogenomics: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Contents:

De Novo Sequencing of Peptides from Tandem Mass Spectra and Applications in Proteogenomics

Genome Annotation

Comprehensive Peptide Mapping is Crucial for Proteogenomics and Proteomics

A Review of Protein Inference

From Gene to Whole Cell: Modelling, Visualization, and Analysis

Introduction to Integrated Proteogenomic Pipeline for Dealing with Pathogenic Missense SNPs

Discovering Novel Proteoforms using Proteogenomic Workflows within the Galaxy Bioinformatics Platform

Comparative Proteomics of Bacteria under Stress Conditions

The Functional Comparison of Eukaryotic Proteomes: Implications for Choosing an Appropriate Model Organism to Probe Human Biology

Sample Preparation for Proteogenomics of Aquatic Invertebrates

Proteogenomics for Non-Model Ocean-Derived Fungi

Deciphering Cancer Complexity: Integrative Proteogenomics and Proteomics Approaches for Biomarker Discovery

Biomarker Discovery via N-Glycoproteomics

Proteogenomic Approaches for Diseasome Studies

Comparative Proteogenomic Approaches for Mapping the Global Proteome of the Unsequenced Leishmania Vector Phlebotomus papatasi

A Proteogenomic Approach for the Identification of Virulence Factors in Leishmania Parasites

Moving Toward Metaproteogenomics: A Computational Perspective on Analyzing Microbial Samples via Proteogenomics

Evaluation of Eukaryotic mRNA Coding Potential.

ISBN:

9781071641521

1071641522