Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases / edited by Namita Agrawal.

Format:

Book

Contributor:

Agrawal, Namita, editor.

Language:

English

Subjects (All):

Metabolism.

Nervous system--Diseases.

Nervous system.

Therapeutics.

Internal medicine.

Medicine--Research.

Medicine.

Biology--Research.

Biology.

Natural products.

Neurological Disorders.

Internal Medicine.

Biomedical Research.

Natural Products.

Local Subjects:

Metabolism.

Neurological Disorders.

Therapeutics.

Internal Medicine.

Biomedical Research.

Natural Products.

Physical Description:

1 online resource (442 pages)

Edition:

1st ed. 2024.

Place of Publication:

Singapore : Springer Nature Singapore : Imprint: Springer, 2024.

Summary:

This book presents a systematic and extensive understanding about metabolic alterations affecting multiple aspects of different neurodegenerative diseases (NDDs), such as Alzheimer’s, Parkinson’s, Huntington’s disease, SCAs, SBMA, DRPLA, ALS, Freidrich Ataxia etc. The book also illustrates cellular and molecular mechanisms behind the key neurodegenerative diseases and further expands on concept of unique and developing biomarkers associated with the onset and progression of NDDs. Additionally, it elaborates on the concept of latest imaging tools to monitor state of NDDs and accordingly develop therapeutic approaches entailing phytochemicals in the management of metabolic alterations associated with NDDs that ultimately suppresses course of devastating NDDs. The book aids to improve the overall understanding about the NDD and involvement of metabolic disorder as a major factor for indisposition of the disease. Therefore, suggesting that targetting metabolic variations by phytochemicals can combat NDD related symptoms for the betterment of impacted patients. While introducing cellular and molecular mechanisms and the treatment regimen under the umbrella of metabolism in several NDDs, the book covers major aspects of understanding the metabolic basis of NDDs, its implications, and treatment. This will inflate the readers' understanding about this particular area and guide those working in this domain, be it a researcher or clinicians,to choose or design effective therapeutic strategies to curb metabolic alterations linked with these disorders. This book will not only contribute towards improving the overall state of the challenged individuals but will also bring new hope towards improving the quality of lives of affected patients.

Contents:

Chapter 1: An Overview of Neurodegenerative Disorders

Chapter 2: Mechanism underlying major neurodegenerative disorders

Chapter 3: Involvement of metabolic paradigm in progression of neurodegenerative diseases

Chapter 4: Glial cell metabolism and neurodegenerative diseases: The current perspective

Chapter 5: Altered glucose homeostasis in neurological disorders

Chapter 6: Lipid Metabolism: Key Determinant in Neurodegenerative Diseases

Chapter 7 - Dysregulated peripheral metabolism in neurodegenerative disorders

Chapter 8- Protein Metabolism: Critical factors implicated in neurodegenerative diseases

Chapter 9 - Altered RNA metabolism in neurodegenerative disorders

Chapter 10: Unveiling RNA dysfunction: A key player in neurodegeneration

Chapter 11: Emerging Relationship between the Gut Microbiota and Neurodegenerative Disorders

Chapter 12- Signaling Pathways in Neurodegenerative diseases

Chapter 13: An overview of imaging techniques for diagnosis of debilitating neurodegenerative diseases

Chapter 14: Novel Metabolic Biomarkers and Therapeutic Strategies in Neurodegenerative Diseases

Chapter 15: Phytochemicals: Promising alternatives for metabolic regulation in neurodegenerative diseases.

Notes:

Includes bibliographical references.

ISBN:

981-9742-88-9