Screening for breast cancer : a comparative effectiveness review for the U.S. Preventive Services Task Force / Jillian T. Henderson [and four others].

Format:

Book

Author/Creator:

Henderson, Jillian T., author.

Series:

Evidence syntheses ; Number 231

Language:

English

Subjects (All):

Breast--Cancer--Research.

Breast.

Physical Description:

1 online resource (x, 234 pages) : illustrations.

Other Title:

Screening for breast cancer

Place of Publication:

Rockville, MD : Agency for Healthcare Research and Quality, 2024.

Summary:

We conducted this systematic review to support the U.S. Preventive Services Task Force (USPSTF) in updating its recommendations on breast cancer screening. Our review addresses the comparative effectiveness of breast cancer screening for improving health outcomes. The review compares different strategies regarding when to screen (e.g., age to start/stop screening, screening interval), screening modalities (e.g., digital breast tomosynthesis [DBT] versus digital mammography [DM]), supplemental screening, or screening strategies defined by breast cancer risk markers.

Contents:

Acknowledgments

Structured Abstract

Chapter 1. Introduction

Purpose

Condition Background

Rationale for Screening and Current Clinical Practices

Previous Evidence Reviews

Previous USPSTF Recommendations

Chapter 2. Methods

Scope and Purpose

Key Questions and Analytic Framework

Data Sources and Searches

Study Selection

Quality Assessment and Data Abstraction

Data Synthesis and Analysis

Grading the Strength of the Body of Evidence

Contextual Questions

Expert Review and Public Comment

USPSTF Involvement

Chapter 3. Results

Literature Search

KQ1. What Is the Comparative Effectiveness of Different Mammography-Based Screening Strategies on Breast Cancer Morbidity and Mortality?

KQ2. What Is the Comparative Effectiveness of Different Mammography-Based Screening Strategies on the Incidence and Progression to Advanced Breast Cancer?

KQ3. What Are the Comparative Harms of Different Breast Mammography-Based Cancer Screening Strategies?

Chapter 4. Discussion

Overall Summary of Evidence

Inequities in Breast Cancer Incidence and Outcomes (CQ1)

Additional Findings From Original Effectiveness Trials (CQ2)

Risk Assessment Tools to Personalize Breast Cancer Screening (CQ3)

Patient Perspectives on Balance of Benefits and Harms of Screening (CQ4)

Breast Cancer and DCIS Treatment Harms (CQ5)

Limitations of Our Review

Limitations of the Evidence and Future Research Needs

Conclusions

References

Appendices

Appendix A. Foundational Trial Evidence From 2016 USPSTF Review

Appendix B. Detailed Methods

Appendix C. Included Studies

Appendix D. Excluded Studies

Appendix E. Additional Intervention Details on Included Trials and NRSIs

Appendix F. Evidence Tables

Appendix G. Detailed Methods and Results of Screening Harms

Appendix H. Ongoing Studies.

Notes:

Description based on publisher supplied metadata and other sources.