Handbook of the Extracellular Matrix : Biologically-Derived Materials / edited by F. Raquel Maia, J. Miguel Oliveira, Rui L. Reis.

Format:

Book

Author/Creator:

Maia, F. Raquel.

Contributor:

Oliveira, J. Miguel.

Reis, Rui L.

Series:

Biomedical and Life Sciences Series

Language:

English

Subjects (All):

Biomaterials.

Cells.

Biomedical engineering.

Proteins.

Biomaterials-Cells.

Biomedical Engineering and Bioengineering.

Biomaterials-Proteins.

Biomedical Materials.

Local Subjects:

Biomaterials-Cells.

Biomedical Engineering and Bioengineering.

Biomaterials-Proteins.

Biomaterials.

Biomedical Materials.

Physical Description:

1 online resource (1322 pages)

Edition:

1st ed. 2024.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2024.

Summary:

This book comprises of 6 sections covering the fundamentals of the extracellular matrix, as well as the development and challenges of using biologically-derived materials, and its advanced biomedical applications. The first section is dedicated to the extracellular matrix, while the other 5 sections are each dedicated to a particular type of material. This book reports the fundamentals of the extracellular matrix and its impact in the development of innovative materials; provides an overview of the advanced methodologies to develop biologically-derived materials; and describes the challenges of the synthesis and processing of the different materials. Furthermore, it presents the biological activities, structural and physicochemical properties of such materials, and the modification methods pursued to improve their inherent properties. The wide range of advanced applications are covered as well, including the combination with emerging technologies, underlyingtissue-engineered scaffolding, drug delivery systems, 3D in vitro tissue and cancer models, 3D bioprinted models, bioinks, and more. This reference work serves as a core reference for multidisciplinary students (undergraduates and Ph.D. students) and a wide range of established researchers and professionals working in the medical field, e.g., orthopaedics, radiology, dentistry, and cancer.

Contents:

Extracellular matrix composition

The role of fibrous networks on the extracellular matrix mechanical properties

Extracellular matrix structural features

Extracellular matrix bioactive molecules and cell behavior modeling

Mechanotransduction role at gene expression levels

Extracellular matrix structure regulates local cell-matrix biomechanics

Extracellular matrix isolation: sources and methods

Extracellular matrix and its involvement in tissue generation

Strategies for mimicking extracellular matrix

Extracellular matrix remodeling on cancer progression.

ISBN:

9783031563638

3031563638

OCLC:

1450308151