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Antiprotozoal Drug Development and Delivery / edited by Alane Beatriz Vermelho, Claudiu T. Supuran.

Springer eBooks EBA - Springer Chemistry and Material Science Collection 2022 Available online

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Format:
Book
Contributor:
Supuran, Claudiu T., editor.
Vermelho, Alane Beatriz, editor.
Series:
Topics in Medicinal Chemistry, 1862-247X ; 39
Language:
English
Subjects (All):
Pharmaceutical chemistry.
Synthetic biology.
Medical microbiology.
Parasitology.
Medicine, Preventive.
Health promotion.
Bioinformatics.
Medicinal Chemistry.
Synthetic Biology.
Medical Microbiology.
Health Promotion and Disease Prevention.
Computational and Systems Biology.
Local Subjects:
Medicinal Chemistry.
Synthetic Biology.
Medical Microbiology.
Parasitology.
Health Promotion and Disease Prevention.
Computational and Systems Biology.
Physical Description:
1 online resource (333 pages)
Edition:
1st ed. 2022.
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2022.
Summary:
This book reviews new promising drug targets for Neglected Tropical Diseases (NTDs), with a special focus on antiprotozoal drugs against trpyanosomatids Trypanosoma cruzi and Leishmania spp. The book offers a comprehensive overview of the most recent studied targets, and it outlines classical and new treatments and delivery strategies. Expert contributors describe new methods of analysis and bio-prospecting for new compounds, and provide a critical perspective of the translational process used in the research and development of new drug candidates. The book will appeal not only to researchers, students and professionals interested in drug development to protozoan diseases, but also to medicinal chemists in general.
Contents:
Classical and Modern Drug Treatments for Leishmaniasis
Saponins as Potential Antiprotozoa Agents
Chagas Disease: Drug Development and Parasite Target
Targeting carbonic anhydrases from Leishmania spp. and Trypanosoma cruzi as a strategy to obtain new drugs
New Compounds for the Management of Trypanosoma brucei Infection
Polyamine and Trypanothione Pathways as Targets for Novel Antileishmanial Drugs
Nano and Microstructured Delivery Systems for Current Antileishmanial Drugs
Pharmacological Treatment of Malaria
η-Class Carbonic Anhydrases as Antiplasmodial Drug Targets: Current State of the Art and Hurdles to Develop New Antimalarials
Management of Entamoeba histolytica Infection: Treatment Strategies and Possible New Drug Targets
Trichomonas vaginalis Pharmacological Treatment
Beta-Carbonic Anhydrase from Trichomonas Vaginalis as New Antiprotozoan Drug Target
Drugs for the treatment of toxoplasmosis
Challenges and promises for obtaining new antiprotozoal drugs – what’s going wrong?
Notes:
Description based upon print version of record.
Other Format:
Print version: Vermelho, Alane Beatriz Antiprotozoal Drug Development and Delivery
ISBN:
3-031-06850-5
OCLC:
1333445629

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