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Animal-centric care and management : enhancing refinement in biomedical research / edited by Dorte Bratbo Sørensen, Sylvie Cloutier, Brianna N. Gaskill.

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Format:
Book
Contributor:
Sørensen, Dorte Bratbo, editor.
Cloutier, Sylvie, editor.
Gaskill, Brianna, editor.
Language:
English
Subjects (All):
Laboratory animals--Care.
Laboratory animals.
Animal welfare.
Physical Description:
1 online resource (205 pages)
Edition:
1st ed.
Place of Publication:
Boca Raton, Florida ; London, England ; New York : CRC Press, [2021]
Summary:
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch's definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.
Contents:
Cover
Half Title
Title Page
Copyright Page
Table of Contents
Preface
Editors
List of Contributors
Chapter 1 Human-Animal Interactions
Introduction
Defining Human-Animal Interactions
Impacts of Human-Animal Interactions
Ecological Framework
Animals
Animal Welfare Theoretical Framework
Harms for Animals
Benefits for Animals
Humans
Human Theoretical Frameworks
Harms for Humans
Benefits for Humans
Recommendations
Principles
Changing Human Behavior to Improve Animal Welfare
Limitations and Future Work
Conclusion
References
Chapter 2 A Culture of Care
Background: Why a "Culture of Care?"
What Is the Culture of Care?
Implementing a Culture of Care
The People Perspective
The 3Rs Perspective
The Good Science Perspective
Methods and Tools to Shape a Culture
The Role of Local Ethics or Animal Care and Use Committees
Culture of Challenge
Assessing the Culture of Care
What Matters
Surrogate Markers
Building a Survey
Assessing the Impact of the Culture of Care
Promoting the Culture of Care
National Meetings Arranged by Authorities
Scientific Congresses and Meetings
Organizations and Networks
Other Opportunities to Promote the Culture of Care
Chapter 3 Animal Emotions and Moods: Why They Matter
Panksepp's Seven Core Emotions
CARE
GRIEF
PLAY
LUST
SEEKING
FEAR
RAGE
Summary of the Core Emotional Systems
Core Affect Space
Moods
Welfare and Positioning in Core Affect Space
Combining the Two Models of Emotion
Chapter 4 Abnormal Behavior
Abnormality
Why We Should Care about Abnormal Behaviors
Maladaptive or Malfunctional?
Species Differences
Abnormal Repetitive Behavior Prevention.
Abnormal Repetitive Behavior Treatment
Chapter 5 Animal Learning: The Science behind Animal Training
Learning Theories
Stimuli and Generalization
Learning
Non-Associative Learning
Sensitization and Habituation
Associative Learning
Classical Conditioning
The Effect of Salience and Context
Extinction in Classical Conditioning
Operant Conditioning
Extinction in Operant Conditioning
Schedules of Reinforcement
Effect of Positive Reinforcement in Training
Effect of Positive Punishment and Negative Reinforcement in Training
Chapter 6 Animal Training: The Practical Approach
The ABC of Animal Training
The Consequences of Behavior
The Reinforcers
The Aversives
The Importance of Timing, Criteria, and Rate of Reinforcement
Timing
Criteria
Rate of Reinforcement
Getting the Behavior
Capturing
Targeting
Luring and Baiting
Shaping
How to Get Started
Incorrect Responses and Unwanted Behaviors
Incorrect Responses
Unwanted Behavior: Aggression, Frustration, and Fear
Unwanted Behavior: Persistent or Progressing Incorrect Responding
How to Deal with Incorrect Responses
How to End a Session
Creating a Balance
Animal Training in Laboratory Animal Science: Challenges and Perspectives
Acknowledgment
Chapter 7 The Zebrafish
The Basics: Biological Health
Environmental Conditions and Natural Behavior
Zebrafish Life in the Wild
Recreating the Natural Habitat in the Laboratory
Psychological and Emotional Well-Being
Special Considerations
Strains
Human-Animal Interaction
Restrictive Types of Research
Chapter 8 The Mouse
The Animal
Cognitive Abilities
Emotions
The Environment
How to Enrich
Practical Enrichments.
Handling
Handling from the Animal's Perspective
Handling from the Handler's Perspective
Refining Mouse Handling in the Laboratory
Practical Considerations for Non-Aversive Handling
Standardizing Non-Aversive Handling in Research
Further Considerations on Laboratory Mouse Welfare: Where Do We Go from Here?
Chapter 9 The Rat
Free-Ranging Rats: Who Are They?
Housing for Rats in Laboratories
A Historical Perspective
Current Knowledge
Shelters
Exercising and Mobility
Complexity
Recommendations for Implementation
Relationships with Rats in Laboratories
Chapter 10 The Rabbit
General Background
Environment
Social Needs
Social Housing
Handling
Human-Animal Bond
Training
Acknowledgments
Chapter 11 The Dog
Dog Senses and Cognition
The Housing Environment
Enrichment in the Dog Laboratory Facility
Handling and Management
Treating Dogs as Individuals
Chapter 12 The Non-Human Primate
Basic Biology and Behavior
Social Dynamics and Group Constellations
Macaques
Marmosets and Tamarins
Social Housing of Primates in Captivity
Foraging and Food Enrichment
Socialization and Training
Chapter 13 The Pig
The Pig
Characterization: Morphology, Domestication, and Breeds
The Biology and Natural Behavior of the Pig
Cognitive and Emotional Abilities
An Environment Designed for Comfort
An Environment with Enrichment
A Social Environment
Behavioral Management (Handling, Habituation, and Training)
Where to Go Next?.
References
Index.
Notes:
Description based on print version record.
ISBN:
9780429059544
042905954X
9780429602054
0429602057
OCLC:
1197760384

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