Bioreactors : analysis and design / Professor Tapobrata Panda.

Format:

Book

Author/Creator:

Panda, Tapobrata, author.

Series:

McGraw-Hill's AccessEngineering

Language:

English

Subjects (All):

Bioreactors.

Bioreactors--Design.

Genre:

Electronic books.

Physical Description:

1 online resource

Edition:

First edition.

Place of Publication:

New York, N.Y. : McGraw-Hill Education, [2011]

Language Note:

In English.

Summary:

"In recent times, the field of Biology has seen many changes and advancements. This evolution makes a good knowledge about the bioreactor and its operation inevitable for all professionals and students working in this area. Bioreactors: Analysis and Design, arguably the first of its kind, will address all the issues faced by this group. The book begins with an overview of biological reactions, elements of bioreactor design, and fundamentals of mass and energy balances in biological reactions. It discusses in detail the important bioreactors, viz., air-lift reactor, reactors for animal cell processes, and reactors for plant cell processes. Also, CFD in bioreactors is discussed and numerous numerical problems are provided throughout for better explanation of the processes. The book also covers the mechanical design considerations for the various kinds of bioreactors. With its comprehensive coverage, this book would be useful for researchers, teachers, and students working in the area of bioreactors alike.".

Contents:

A. Dedication

B. Preface

C. Acknowledgements

D. Author's profile

1. Introduction

Overview of biological reactions

Elements in bioreactor design

Rate expression in biological systems

Basic concept of energy transfer

Basic concept of mass balance

Exercises

References

Appendix 1

References to appendix 1

2. Understanding of bioreactors

What is a bioreactor?

Why should we study bioreactors?

Development of bioreactors

Purpose and importance of bioreactors

Other bioreactor configurations

Bioreactor development for solid-state fermentation (SSF)

Classification of bioreactors

Bioreactors for animal cell cultivation

Bioreactors for plant cell culture

Bioreactors for immobilized system

Sterilization bioreactors

Bioreactors used in different areas of environmental control and management

Bioreactors used for combined reactions and separation

Further reading

3. Bioreactor operation

Introduction

Common operations of bioreactor

Selection/identification of other common factors necessary for smooth operation of bioreactors

Spectrum of basic bioreactor operations

Reactor operation for immobilized systems

Operation of animal cell bioreactors

Operation of bioreactors for plant cell culture

Reactors for waste management

Appendix 3

4. Biochemical aspect of bioreactor design

Organization of this chapter

Introduction to section a: part 1

Introduction to section a: part 2

Plug flow tubular reactor (PFTR)

Recycle bioreactors

Combination of bioreactors

Semi-continuous bioreactors

Introduction to section B

Input to kinetic modeling of enzyme reactors

Example problems

5. Analysis of non-ideal behavior in bioreactors

Non-ideal parameters

Residence time distribution?some aspects of macro mixing

Some exercise for RTD of ideal systems (ideal bioreactors)

Moments of the distribution

E(t) or f(t) and the bioreactor design

Models for non-ideal flow

Multi parameter models

Application of RTD based models to non-ideal bioreactors

Drawbacks of classical RTD measurements

Transient behavior in bioreactors

Stability analysis for continuous flow bioreactor with substrate inhibition

Phase plane analysis

The bifurcation analysis

References.

6. Bioreactor modeling

Model?what is it?

Definition of lumped and distributed parameter models

Introduction to a few terminologies and theorems

Modeling principles

Steps in modeling

Fundamental laws used in process modeling

First?order systems

Second-order systems

Complexity of the model

Parameter sensitivity

Appendix 6

7. Transport processes in bioreactors

Heat transfer

Other parameters influencing transfer operations

8. Controls in bioreactors

Control tasks in a bioreactor system

Instrumentation to control a bioreactor

Controlled variables and measurement devices

Procedure for design of efficient control systems

Conventional control techniques

Advanced control techniques

Consistency checks on measurements

Adaptive online optimizing control of bioreactor system

Appendix 8

9. Case studies

Design of packed bed bioreactor

Airlift bioreactors

Hollow fiber bioreactor (HFBR)

Plant cell bioreactor

Design of bioreactors for solid state fermentation (SSF)

Mammalian cell bioreactor design

Appendix 9

10. Application of computational fluid dynamics in bioreactor analysis and design

Fluid dynamic modeling

Simulation

Appendix 10

11. Scale-up of bioreactors

Additional scale-up problems in bioreactors

Criteria of scale-up

Similarity criteria

Scale-up methods

Generalized approaches to scale-up in combination of methods

Examples

12. Mechanical aspects of bioreactor design

Requirements for construction of a bioreactor

Guidelines for bioreactor design

Bioreactor vessels

Agitator assembly

Appendix 12.

Notes:

Includes bibliographical references and index.

Electronic reproduction. New York, N.Y. : McGraw Hill, 2011. Mode of access: World Wide Web. System requirements: Web browser. Access may be restricted to users at subscribing institutions.

Description based on cover image and table of contents, viewed on Mar. 24, 2015.

Other Format:

Print version: Bioreactors : analysis and design.

ISBN:

9780070704244 (print-ISBN)

0070704244 (print-ISBN)

OCLC:

907907002

Access Restriction:

Restricted for use by site license.