Photochemical and Electrochemical Activation Strategies of C(sp3)-Based Building Blocks for Organic Synthesis / by Su Yong Go.

Format:

Book

Author/Creator:

Go, Su Yong, author.

Geun Lee, Hong, author.

Series:

Springer Theses, Recognizing Outstanding Ph.D. Research, 2190-5061

Language:

English

Subjects (All):

Electrochemistry.

Photochemistry.

Catalysts.

Catalysis.

Materials.

Catalyst Synthesis.

Catalytic Materials.

Local Subjects:

Electrochemistry.

Photochemistry.

Catalyst Synthesis.

Catalytic Materials.

Physical Description:

1 online resource (185 pages)

Edition:

1st ed. 2024.

Place of Publication:

Singapore : Springer Nature Singapore : Imprint: Springer, 2024.

Summary:

This book addresses novel C(sp3)-C(sp2) and C(sp3)-heteroatom bond-forming reactions. Two strategies are given in the book using photoredox or electrochemical methods. The first strategy describes that the hydroalkylation of alkynes via photoredox-mediated Ni/Ir dual catalysis produces trisubstituted alkenes as versatile synthetic building blocks for the synthesis of pharmaceutical agents and natural products. High regioselectivity and E/Z-selectivity were achieved by introducing silyl groups that can provide steric and electronic effects to these selectivities with extensive opportunities for post-functionalization. The second strategy enables the development of C(sp3)-heteroatom bond-forming reactions through the electrochemical activation of C(sp3)-B bonds. The bonding of heteroatoms to carbon atoms has been an enduring subject of investigation for organic chemists. The function of most molecules is mainly determined by heteroatoms attached to the carbon atom, although the backbone structure of organic compounds comprises carbon fragments.

Contents:

Part I. C(sp2)-C(sp3) Bond Formation Reactions Enabled by Photoredox/Nickel Dual Catalysis

Chapter 1. The Key Concepts and Strategy in Photoredox/Nickel Dual Catalysis and Application to C-C Bond Formation Reactions

Chapter 2. Highl Regioselective and E/Z Selective Hydroalkylation of Alkyne via Photoredox Mediated Ni/Ir Dual Catalysis

Part II. Development of C(sp3)-Heteroatom Bond-Forming Reactions via Electrochemical Activation of C(sp3)-B Bonds and Follow-up Projects

Chapter 3. Recent Achievements of C(sp3)-Heteroatom Bond Formation in Electroorganic Synthesis and History of C(sp3)-B Bond Activation

Chapter 4. Introduction of Heteroatoms to Alkyl Carbocations Generated from Alkylboron Reagents via Electrochemical Activation

Chapter 5. Functionalization of Alkylboron Compounds Under Other Reaction Conditions.

Notes:

Includes bibliographical references.

ISBN:

981-9989-94-9