Cervical cancer screening / International Agency for Research on Cancer.

Format:

Book

Author/Creator:

International Agency for Research on Cancer, author, issuing body.

Language:

English

Subjects (All):

Cervix uteri--Cancer.

Cervix uteri.

Physical Description:

1 online resource

Place of Publication:

Lyon, France : International Agency for Research on Cancer, 2022.

Summary:

A Working Group of 27 independent international experts, convened by the International Agency for Research on Cancer (IARC) between June and October 2020, reviewed the scientific evidence and assessed the cancer-preventive and adverse effects of various methods of screening for cervical cancer. Cervical cancer is the fourth most commonly diagnosed cancer type in women worldwide, and the fourth most common cause of cancer death in women. This publication is an important update of the previous IARC Handbook on cervical cancer screening (Volume 10, published in 2005). Volume 18 provides evidence-based evaluations of the effectiveness of five methods of cervical cancer screening in reducing cervical cancer incidence and/or mortality. The Working Group also reviewed the body of evidence and provided conclusive statements on the comparative effectiveness of those screening methods that are established to reduce cervical cancer incidence and/or mortality. In addition, the Working Group provided an updated literature review on the determinants of participation in screening programmes and on emerging techniques, as well as on the different categories of women at differential risk and the surveillance strategies for such women. This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Cancer-Preventive Strategies, which met remotely, 12-16 October 2020.

Contents:

Note to the Reader

List of Participants

Preamble - Secondary Prevention

General Remarks

List of Abbreviations

Glossary

1. Cervical Cancer

1.1. Global cervical cancer burden

1.2. Cervical neoplasia

References

2. Cervical Cancer Screening Programmes

2.1. Introduction

2.2. Availability and use of cervical cancer screening worldwide

2.3. Quality assurance of screening programmes

3. Participation in Screening for Cervical Cancer

3.1. Negative and positive determinants of participation

3.2. Interventions to increase screening participation

4. Preventive and Adverse Effects of Cervical Cancer Screening

4.1. Methodological issues

4.2. Screening by Visual Inspection

4.3. Cytological Methods

4.4. HPV testing

4.5. Colposcopy

4.6. Emerging technologies

5. Screen-and-treat approach and women at differential risk

5.1. Screen-and-treat approach

5.2. Screening surveillance of women at differential risk

6. Summary

6.1. Cervical cancer

6.2. Cervical cancer screening programmes

6.3. Participation in screening for cervical cancer

6.4. Preventive and adverse effects of cervical cancer screening methods

6.5. Screen-and-treat approach and women at differential risk

7. Evaluations and comparison statements

7.1. Visual inspection with acetic acid

7.2. Conventional cytology

7.3. Liquid-based cytology

7.4. HPV nucleic acid testing

7.5. Cytology based on Romanowsky-Giemsa staining

7.6. HPV DNA testing versus VIA

7.7. HPV DNA testing versus cytology

7.8. HPV DNA testing alone versus co-testing

7.9. Considerations on related issues

Annex 1. Supplementary material for Section 4.4.7 Triage of women with a positive primary HPV screening test result.

Notes:

Description based on publisher supplied metadata and other sources.