Role of Mast Cells and Probiotics in the Regulation of Intestinal Barrier Function.

Format:

Book

Author/Creator:

Carlsson, Anders.

Series:

Linköping University Medical Dissertations

Linköping University Medical Dissertations ; v.1363

Language:

English

Subjects (All):

Intestinal mucosa.

Mast cells.

Physical Description:

1 online resource (75 pages)

Edition:

1st ed.

Other Title:

Linköping University Medical Dissertations

Place of Publication:

Linköping : Linköping University Electronic Press, 2013.

Summary:

This dissertation by Anders Carlsson explores the role of mast cells and probiotics in regulating intestinal barrier function. The research investigates how stress and inflammation affect the permeability of the intestinal mucosa, which is crucial in preventing harmful substances from entering the body. The study employs in vitro and ex vivo experiments on animal and human tissues to understand the mechanisms involved. The findings indicate that stress impacts the epithelial barrier via vasoactive intestinal polypeptide and mast cells. Probiotics are shown to protect against barrier dysfunction, suggesting a potential therapeutic role in conditions like Crohn's disease and ulcerative colitis. The work aims to enhance understanding of the intestinal barrier's regulation under stress and the beneficial effects of probiotics. Generated by AI.

Contents:

Intro

ABSTRACT

POPULÄRVETENSKAPLIG SAMMANFATTNING

LIST OF PAPERS

Publications outside of this thesis

ABBREVIATIONS

TABLE OF CONTENTS

INTRODUCTION

AIMS

MATERIALS &amp

METHODS

RESULT SUMMARY

DISCUSSION

CONCLUSIONS

ACKNOWLEDGEMENTS

REFERENCES.

Notes:

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

ISBN:

9789175196305

9175196301

OCLC:

927227640