Chronic fatigue syndrome : symptoms, causes, and prevention / Edita Svoboda and Kristof Zelenjcik, editors.

Format:

Book

Contributor:

Svoboda, Edita.

Zelenjcik, Kristof.

Series:

Immunology and immune system disorders.

Immunology and immune system disorders

Language:

English

Subjects (All):

Chronic fatigue syndrome.

Fatigue.

Physical Description:

1 online resource (203 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Biomedical/Nova Science, c2010.

Language Note:

English

Summary:

Chronic fatigue syndrome (CFS) is a complicated disorder characterized by extreme fatigue that doesn't improve with bed rest and may worsen with physical or mental activity. Chronic fatigue syndrome may occur after an infection, such as a cold or viral illness. The onset can also be during or shortly after a time of great stress, or it may come on gradually without a clear starting point or obvious cause. This book discusses new research in CFS, including the effects that CFS may have on immune system responses. The possible implications and prevention of CFS are also explored.

Contents:

CHRONIC FATIGUE SYNDROME SYMPTOMS, CAUSES AND PREVENTION ; CHRONIC FATIGUE SYNDROME SYMPTOMS, CAUSES AND PREVENTION; Contents; Preface; The Immune System in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis; Abstract; Introduction; Definitions of Chronic Fatigue Syndrome; CFS/ME and Viral and Other Infections; Immunological System; T Lymphocyte; B Lymphocytes; Neutrophils; Natural Killer Cells (NK); Discussion; CFS/ME Patients' Lymphocyte Levels; Lymphocyte Function; Llymphocyte response to stimulation; Cytokine production and function; Phagocytic activity; Cytotoxic activity

Changes in activation markersGene Expression in CFS/ME; Interactions between the Immune System and Other Systems in CFS/ME; Immune-neuroendocrine interactions; Interaction between the immune system and the nervous system; Conclusion; References; The NO/ONOO-Vicious Cycle Mechanism as the Cause of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis; Abstract; Introduction; Five Principles; CFS and the First Two Principles; Animal Models; Genetic Studies; Generation of Shared Symptoms and Signs; Specific Signs and Symptoms for CFS and Where to Look for a Specific Biomarker Test

Local Nature of the CFS MechanismGene Expression Studies: Evidence for Role of Cycle Elements; Therapy: Avoiding Infections, Excessive Exercise, Allergens and Other Stressors; Therapy: Agents That Lower NO/ONOO-Cycle Biochemistry; Treatment Protocols with Multiple Agents Lowering NO/ONOO-Cycle Biochemistry; Description of Responses (and Again, Skepticism Should be Maintained); How Can We Obtain Substantial Numbers of Cures?; Summary: CFS as a NO/ONOO-Cycle Disease; References

The Anti-Fatigue Effect of Moderate Cooling: The Evidence, Physiological Mechanisms, and Possible Implications for the Prevention or Treatment of CFSAbstract; Introduction; 2. Body Cooling and Athletic Performance; 3. Possible Mechanisms of the Anti-Fatigue Effect of Cooling; 3.a. Cerebral Serotonin and Fatigue; 3.b. Stress-Response Pathways; 3.c.The Analgesic Effect of Cooling; 3.d. The Reticular Activating System; 3.e. Dopamine and Fatigue; 3.f. The Thyroid and Fatigue; 3.g. Fever and Fatigue; 4. Potential Adverse Effects of Cold Hydrotherapy; 5. Conclusion; References

Chronic Fatigue Syndrome:Metabolic and Electrophysiological Muscle Responses to ExerciseAbstract; Introduction; Biochemical Events; Metabolism; Glycolysis appears inconstantly abnormal; Aerobiosis and oxidative stress are often accentuated; Cell Signalling Pathways on Biochemical Changes; Innate immunity and inflammatory response to exercise; Expression of heat shock proteins; Electrophysiological Muscle Events; Absence of "Central Fatigue"; Altered Muscle Membrane Excitability; Altered Ionic Fluxes Through the Muscle Membrane; Conclusion; References

Characteristic Features of Dysautonomia Distinguishing Chronic Fatigue Syndrome from Fibromyalgia - One Clinic's Experience

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-61122-661-9