Some Drugs and Herbal Products / IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Format:

Book

Author/Creator:

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, author, issuing body.

Series:

IARC monographs on the evaluation of carcinogenic risks to humans ; Volume 108.

IARC monographs on the evaluation of carcinogenic risks to humans, ; 108, volume 108

Language:

English

Subjects (All):

Carcinogenicity testing.

Physical Description:

1 online resource (xii, 422 pages) : illustrations.

Place of Publication:

Lyon, France : International Agency for Research on Cancer, 2014.

Summary:

This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension). Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.

Contents:

Note to the reader

List of participants

Preamble

General remarks

Aloe vera

Goldenseal

Gingko biloba

Kava

Pulegone

Methylene blue

Primidone

Sulfasalazine

Pentosan polysulfate sodium

Triamterene

Hydrochlorothiazide

Pioglitazone and rosiglitazone

Digoxin

List of abbreviations.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

92-832-0174-4