Paraneoplastic neurologic disorders / edited by Bruno Giometto, Sean J. Pittock.

Format:

Book

Contributor:

Giometto, Bruno, editor.

Pittock, Sean J., editor.

Series:

Handbook of clinical neurology ; v. 200.

Handbook of clinical neurology ; volume 200, 3rd series

Language:

English

Subjects (All):

Paraneoplastic syndromes.

Paraneoplastic syndromes--Treatment.

Paraneoplastic Syndromes.

Medical Subjects:

Paraneoplastic Syndromes.

Physical Description:

1 online resource.

Place of Publication:

Amsterdam, Netherlands : Elsevier, [2024]

Summary:

Paraneoplastic Neurological Disorders, Volume 200 covers new, recent descriptions of autoantibodies against neuronal cell surface antigens (only partly associated with paraneoplastic disorders) and the introduction of new immuno-oncological drugs that can contribute to diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. Besides investigating the pathogenetic mechanisms of these disorders, this book also explores what the introduction of new drugs used in immune checkpoint inhibitor cancer therapy are teaching us in terms of immunopathogenesis. Following sections present individual syndromes (phenotypical clinical manifestations) of the CNS, PNS, NMJ, and muscle. Finally, the book investigates the role of antibody markers that differentiate by cytoplasmic, nuclear, and neuronal cell surface reactivities. Side effects of the new immuno-oncological drugs increasingly used in cancer therapy are also covered

Contents:

Introduction and overview of immunopathological mechanisms and future directions / Sean J. Pittock, Bruno Giometto

Changing landscape in the field of paraneoplastic neurology : Personal perspectives over a 35-year career / Josep Dalmau

Pathogenesis and immunopathology of paraneoplastic disorders / Valérie Quinot, Romana Höftberger

Epidemiology of paraneoplastic neurologic syndromes / Robert Kadish, Stacey L. Clardy

Clinical approach to diagnosis of paraneoplastic neurologic syndromes / Francesc Graus

Overview of treatment strategies in paraneoplastic neurological syndromes / Jeroen Kerstens, Maarten J. Titulaer

Evolution of methods to detect paraneoplastic antibodies / Patrick Waters, John R. Mills, Hannah Fox

Paraneoplastic encephalitis / Silvia Casagrande, Luigi Zuliani, Wolfgang Grisold

Autoimmune and paraneoplastic seizures / Barbara Wagner, Sarosh Irani

Paraneoplastic cerebellar and brainstem disorders / Justin R. Abbatemarco, Christian A. Vedeler, John E. Greenlee

Paraneoplastic/autoimmune myelopathies / Mayra Montalvo, Eoin P. Flanagan

Paraneoplastic vision loss / Deena Tajfirouz, John J. Chen

Paraneoplastic movement disorders / Andrew McKeon, Jennifer Tracy

Movement disorders associated with pediatric encephalitis / Russell C. Dale, Shekeeb S. Mohammad

Paraneoplastic neuropathies and peripheral nerve hyperexcitability disorders / Shahar Shelly, Divyanshu Dubey, John R. Mills, Christopher J. Klein

Paraneoplastic autonomic neuropathies and GI dysmotility / Elisabeth P. Golden, Steven Vernino

Myasthenia gravis—Pathophysiology, diagnosis, and treatment / Martijn R. Tannemaat, Maartje G. Huijbers, Jan J.G.M. Verschuuren

Lambert-Eaton myasthenic syndrome / Alexander F. Lipka, Jan J.G.M. Verschuuren

Paraneoplastic myopathies / Andrew L. Mammen

Paraneoplastic antibodies targeting intracellular antigens / Jenny J. Linnoila

Antibodies to neural cell surface and synaptic proteins in paraneoplastic neurologic syndromes / Adrian Budhram, Elia Sechi

Optimizing the diagnostic performance of neural antibody testing for paraneoplastic and autoimmune encephalitis in clinical practice / Adrian Budhram, Eoin P. Flanagan

Paraneoplastic autoimmune neurologic disorders associated with thymoma / Raffaele Iorio, Vanda A. Lennon

Paraneoplastic neurologic manifestations of neuroendocrine tumors / Marco Zoccarato, Wolfgang Grisold

Paraneoplastic neurologic syndrome associated with gynecologic and breast malignancies / Elise Peter, Jérôme Honnorat, Virginie Desestret

Hematologic malignancies and hematopoietic stem cell transplantation / Chiara Briani, Andrea Visentin

Paraneoplastic neurologic syndrome and autoantibody accompaniments of germ cell tumors / M Bakri Hammami, Mohamed Rezk, Divyanshu Dubey

Neurologic manifestations of autoimmunity with immune checkpoint inhibitors / Jennifer A. McCombe, Elia Sechi, Anastasia Zekeridou

Notes:

Includes bibliographical references and index

Online resource; title from PDF title page (ScienceDirect, viewed March 20, 2024)

Other Format:

Print version: Paraneoplastic neurologic disorders

ISBN:

9780128242179

0128242175

OCLC:

1427386571

Access Restriction:

Restricted for use by site license