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Focal Neuropathies [electronic resource].

Elsevier ScienceDirect eBook - Neuroscience 2022 Available

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Format:
Book
Author/Creator:
Chalk, Colin.
Series:
Issn Series.
Issn Series
Language:
English
Physical Description:
1 online resource (314 p.).
Place of Publication:
San Diego : Elsevier, 2024.
Contents:
Intro
Focal Neuropathies
Copyright
Handbook of Clinical Neurology 3rd Series
Foreword
Preface
Contributors
Contents
Chapter 1: Hallmarks of peripheral nerve injury and regeneration
Introduction
Peripheral nerve anatomy
Nerve injuries and hallmarks of regeneration
Wallerian and Wallerian-Like Degeneration and Path-Clearing
Axon and myelin degeneration
Regenerative path-clearing
Cellular and Molecular Reprogramming of the Distal Nerve Stump
The dynamics of SCs and macrophages
Local Translation, Intra-Axonal Transport, and Axon Guidance
Local translation and axon guidance
Molecular guidance and preferential reinnervation of targets
Intra-axonal transport
Axon myelination
Regenerative Priming of Neurons
Regeneration associated genes
Satellite glial cells and resident macrophages
Growth suppressors and neuron loss
Molecular Mechanisms for Nerve Regeneration and Potential Therapeutic Opportunities
Pharmacological opportunities for nerve repair
Nonpharmacological opportunities for nerve repair
Summary
Acknowledgments
Reference
Chapter 2: The role of imaging in focal neuropathies
Introduction
Basic Principles of Nerve Ultrasound
Basic Principles of Magnetic Resonance Neurography
Ultrasound or MR Neurography
Imaging of the Median Nerve
Imaging of the Ulnar Nerve
Imaging in Leprosy
Imaging of the Radial Nerve
Imaging of the Brachial Plexus
Imaging in Neuralgic Amyotrophy
Imaging of the Common Fibular Nerve
Imaging of the Tibial Nerve
Imaging of the Sciatic Nerve, Femoral Nerve, and Lumbosacral Plexus
Imaging of the Lateral Femoral Cutaneous Nerve
Imaging in Peripheral Nerve Trauma
Imaging of Peripheral Nerve Tumors
Imaging in Inflammatory Neuropathies
Conclusions
References
Chapter 3: The role of electrodiagnosis in focal neuropathies
Role of EDX Testing in Mononeuropathies
Pathophysiology of Nerve Injury Relevant to EDX Findings
Role of NCS in Mononeuropathies
Motor NCS
Motor NCS in focal demyelination
Conduction velocity slowing
Conduction block
Temporal dispersion
Axon loss
Role of Short-Segment Stimulation ``Inching ́́Motor NCS Studies
Sensory NCS
Limitations and Pitfalls of NCS
Technical and physiologic pitfalls mimicking mononeuropathies
Limitations of proximal NCS techniques
Sensitivity in mild or intermittent symptoms
Errors in localization
Role of Needle Electromyography (EMG) in Mononeuropathies
Types and Significance of Needle EMG Abnormalities
Fibrillation potentials
Fasciculation potentials
Complex repetitive discharges (CRDs)
Voluntary motor unit potentials (MUPs) in mononeuropathies
Reduced recruitment
MUP morphology changes
Limitations and Pitfalls of Needle EMG
Errors in localization
Notes:
Description based upon print version of record.
Role of EDX in Grading Severity of Mononeuropathies
Other Format:
Print version: Chalk, Colin Focal Neuropathies
ISBN:
9780323901093
0323901093
OCLC:
1432602622
Access Restriction:
Restricted for use by site license.

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