The promise and perils of next-generation DNA sequencing at birth : proceedings of a workshop--in brief / Kathryn C. Asalone, Sarah H. Beachy, Michael Zierler.

Format:

Book

Author/Creator:

Asalone, Kathryn C., author.

Beachy, Sarah H., author.

Zierler, Michael, author.

Language:

English

Subjects (All):

Infant, Newborn.

Physical Description:

1 online resource (1 PDF file (12 pages))

Other Title:

promise and perils of next-generation DNA sequencing at birth

Place of Publication:

Washington, DC : National Academies Press, 2023.

Summary:

Pilot programs are employing whole genome sequencing and whole exome sequencing during the newborn phase both within the United States and internationally. While sequencing offers the opportunity to screen for treatable but not clinically evident conditions early in a childs life, it raises a host of ethical, legal, and social questions for experts, including parents, to consider. The National Academies Roundtable on Genomics and Precision Health hosted experts from health care, industry, academia, the federal and state governments, and patient and consumer advocacy groups for a June 2023 workshop. Participants explored the potential benefits and harms, data security, and health equity considerations for the widespread utilization of newborn genome sequencing in the U.S. This publication summarizes the presentation and discussion of the workshop.

Contents:

KEYNOTE ADDRESS

CONSIDERING THE BENEFITS AND RISKS OF NEWBORN GENOME SEQUENCING

IMPLEMENTING NEWBORN GENOME SEQUENCING PROGRAMS: LESSONS LEARNED FROM PILOT PROJECTS

NC NEXUS

IMPLEMENTING NEWBORN SEQUENCING AT SCALE

WORKING WITH FAMILIES: RESPONSIBLE AND EQUITABLE DEPLOYMENT

NEWBORN SEQUENCING AND THE FUTURE OF PRECISION HEALTH

FINAL REFLECTIONS AND CLOSING REMARKS

REFERENCES.

Notes:

Description based on publisher supplied metadata and other sources.