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Fundamental Principles of Oxidative Stress in Metabolism and Reproduction : Prevention and Management.
- Format:
- Book
- Author/Creator:
- Alam, Faiza.
- Language:
- English
- Subjects (All):
- Oxidative stress.
- Free radicals (Chemistry).
- Physical Description:
- 1 online resource (370 pages)
- Edition:
- 1st ed.
- Place of Publication:
- San Diego : Elsevier Science & Technology, 2024.
- Summary:
- This book, edited by Faiza Alam and Rehana Rehman, delves into the fundamental principles of oxidative stress and its impact on metabolism and reproduction. It presents a comprehensive examination of oxidative stress, exploring its sources, mechanisms, and effects on various bodily functions and diseases. Key topics include the role of reactive oxygen species (ROS), antioxidants, and the implications of oxidative stress on health conditions such as diabetes, cardiovascular diseases, and reproductive disorders. The book is intended for researchers, healthcare professionals, and students in the fields of biology, medicine, and health sciences, aiming to provide insight into prevention and management strategies for oxidative stress-related conditions. Generated by AI.
- Contents:
- Front Cover
- Fundamental Principles of Oxidative Stress in Metabolism and Reproduction
- Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management
- Dedication
- Contents
- Contributors
- Preface
- Acknowledgments
- I - Overview: Cause and mechanisms
- 1 - Introduction to oxidative stress
- Oxidative stress
- What is oxidative stress?
- Redox hypothesis
- Sources of ROS that influence the human body
- Exogenous sources/factors: These include changes in the environment that increase ROS production in cells such as (Antunes ...
- Endogenous sources/factors: Endogenous or intracellular factors include
- Influence of ROS on body functions
- OS and the defense of the human body
- What is an "antioxidant"?
- Types of antioxidants
- Antioxidants-Mechanism of protection
- Influence of oxidative stress: From health to disease
- OS and cardiovascular diseases
- Reactive species (ROS/RNS) and OS in joint problems
- OS and the brain
- OS and the eyes
- OS and the respiratory system
- OS and the skin
- OS and renal functions
- OS and gastrointestinal tract
- OS and the immune system
- OS and multiple organs
- Diagnosis: Biomarkers of OS
- Antioxidant defense and therapeutic implications
- Prevention
- References
- 2 - Role of free radicals in normal human physiology
- Overview of oxidative stress
- Free radicals
- Superoxide anion
- Hydrogen peroxide
- Hydroxyl radical
- Peroxyl radical
- Singlet oxygen radical
- Hypochlorous acid
- Nitrous oxide
- Enzymatic and nonenzymatic reactions of free radicals
- Free radicals, antioxidant, and tissue injuries
- Categories of defense mechanisms
- Oxidative stress and diabetes mellitus
- Techniques used for the identification of free radicals
- Oxidative stress and mitochondria
- Oxidative stress and inflammation.
- Oxidative stress and chronic inflammatory disorders
- Oxidative stress and infertility
- 3 - Role of diet in the development of oxidative stress
- Introduction to oxidative stress
- Correlation between diet and oxidative stress
- Exercise and oxidative stress
- Scavenger-antioxidants
- Classification of antioxidants
- Neutralizer of free radicals
- Antioxidants
- Cardioprotective eating
- Phytonutrients
- Antioxidant capacity measurement
- Nutritionally mediated oxidative stress
- Carbohydrates
- Fats
- Strategies for decreasing oxidative stress
- Strategies to decrease oxidative stress
- Oxidative stress-induced diseases ameliorating by diet
- Dietary concern
- Conclusion
- 4 - Occupational hazards and oxidative stress
- Introduction
- Definition
- History
- Example at workplaces
- Mechanism of oxidative stress
- Formation of free radicals at the workplace
- Effects to the workers
- Cancer and oxidative stress
- Cardiovascular disease and oxidative stress
- Neurological disease and oxidative stress
- Respiratory disease and oxidative stress
- Rheumatoid arthritis and oxidative stress
- Kidney disease and oxidative stress
- Aging and oxidative stress
- Gastrointestinal tract and oxidative stress
- Reproduction and oxidative stress
- Prevention/management of occupational hazards and oxidative stress
- 5 - Role of radio-frequency electromagnetic waves in causing oxidative stress
- Material and methods.
- Electron microscopy
- RNA extraction
- Results
- Discussion
- 6 - Genetic variations and lifestyle in oxidative stress
- Importance of balancing oxidants and antioxidants
- Genetic variations and oxidative stress
- Role of genetics in the production and metabolism of ROS
- Effect of genetic variations on antioxidant enzymes
- Lifestyle factors and oxidative stress
- Diet and oxidative stress
- Physical activity and oxidative stress
- Environmental toxins and oxidative stress
- Interplay between genetic variations and lifestyle in oxidative stress
- Importance of considering both factors in assessing risk
- Summary of the interaction between genetic variations and lifestyle in oxidative stress
- Importance of a holistic approach to understanding and managing oxidative stress
- Further reading
- 7 - Aging: Generation of oxidative stress
- What is aging?
- Why it is important to know about the processes involved in aging?
- Overview of aging theories
- "Somatic mutation" theory
- Free radical theory/oxidative stress theory
- The cross-linking theory of aging
- Cell and role of organelles in ROS production
- Role of peroxisomes
- Role of endoplasmic reticulum
- Oxidative stress and age-related diseases
- How can we minimize OS?
- Polyphenols in honey
- Polyphenols in blueberries
- Polyphenols in green tea
- Polyphenols in red wine
- Dietary polyphenols in combating aging
- Summary
- II - Systemic effects of oxidative stress
- 8 - Oxidative stress and insulin resistance
- Insulin resistance
- Insulin and insulin signaling
- Pathophysiology of insulin resistance
- Etiology of insulin resistance
- Obesity
- Inflammation
- Mitochondrial dysfunction
- Aging
- Endoplasmic reticulum stress
- Oxidative stress.
- Mechanisms causing insulin resistance by oxidative stress
- Adipokine dysregulation
- NF-kB pathway
- JNK signaling pathway
- Symptoms of insulin resistance
- Complications of insulin resistance
- Role of antioxidants in insulin resistance
- 9 - Oxidative stress and cardiovascular diseases
- Background
- Free radicals involved in cardiovascular diseases
- Mechanism of redox signaling pathway
- What is the link between OS and cardiovascular disease? cause/association
- OS and pathogenesis of cardiovascular disease: The basic mechanism
- The role of endothelium and oxidative stress in cardiovascular disease
- Oxidative stress and hypertension
- Oxidative stress and myocardial damage
- Basis of cardiac failure and arrhythmias
- Oxidative stress and atherosclerosis
- The main contributor to ischemic heart disease
- Antioxidant therapy and drugs used to treat cardiovascular diseases due to oxidative stress
- Conclusion and future perspective
- 10 - Oxidative stress and chronic kidney disease
- Reactive oxygen species
- Enzymatic antioxidants
- Water soluble antioxidants
- Dietary antioxidants
- Ascorbic acid
- Polyphenols-flavonoids
- Endogenous antioxidants
- Lipid-soluble antioxidants
- Trace elements
- Oxidative stress and chronic kidney disease
- Pathogenesis of oxidative stress in CKD
- Uremia and dialysis-related factors
- Diabetes and oxidative stress
- Dyslipidemia and oxidative stress
- Inflammation and oxidative stress
- Biomarkers of oxidative stress in CKD patients
- Clinical implications of oxidative stress in CKD patients
- Oxidative stress and CKD-mediated cardiovascular disease
- Atherosclerosis
- Anemia
- Amyloidosis
- Immunodeficiency.
- Protein-energy wasting syndrome
- Treatment
- N-acetylcysteine
- Vitamin E
- Vitamin C
- Omega-3 fatty acids
- Carnitine
- Coenzyme Q10
- Folic acid
- Newer agents in modulating oxidative stress in CKD
- 11 - Oxidative stress in neurodegenerative diseases
- Alzheimer disease
- Treatment of Alzheimer's disease
- Parkinson's disease
- Treatment of Parkinson's disease
- Amyotrophic lateral sclerosis
- Treatment of amyotrophic lateral sclerosis
- 12 - Oxidative stress, mechanisms of subfertility, and reproductive disorders in females
- Sources of ROS in the female reproductive system
- The role of reactive oxygen species in the normal functions of female reproductive organs
- Impact of oxidative stress on ovarian function
- Ovarian cycle
- Follicular phase
- Ovulatory phase
- Post ovulatory phase
- Corpus luteum formation
- Oxidative stress: Steroidogenesis
- The impact of OS on female reproductive health organs
- Effects on ovary
- Effects on oocyte
- Effects on uterus
- Effects on embryo
- Oxidative stress manifestations as a disease leading to infertility
- Polycystic ovary syndrome
- Endometriosis
- Preeclampsia
- Lifestyle: Oxidative stress and female infertility
- Conclusion and future directions
- 13 - Oxidative stress, mechanisms, and subfertility in male
- Male subfertility
- Oxidative stress definition
- Sources of reactive oxygen stress
- Extrinsic
- Intrinsic
- Physiological role of reactive oxygen stress on spermatozoa
- Pathological effects of reactive oxygen stress on spermatozoa
- Oxidative-induced changes in conventional semen parameters
- Current approach for assessment of reactive oxygen stress markers in sperm and semen
- Direct assays
- Indirect assays.
- Life-style factors associated with high reactive oxygen species and male subfertility.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Part of the metadata in this record was created by AI, based on the text of the resource.
- ISBN:
- 9780443188060
- 0443188068
- OCLC:
- 1429742639
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