An Introduction to the Microbiome in Health and Diseases / Charles Oluwaseun Adetunji [and three others].

Format:

Book

Author/Creator:

Adetunji, Charles Oluwaseun, author.

Series:

The Microbiome in Health and Diseases Series

Language:

English

Subjects (All):

Gastrointestinal system--Microbiology.

Gastrointestinal system.

Digestive System--microbiology.

Gastrointestinal Microbiome.

Microbiota--physiology.

Medical Subjects:

Digestive System--microbiology.

Gastrointestinal Microbiome.

Microbiota--physiology.

Physical Description:

1 online resource (246 pages)

Edition:

First edition.

Place of Publication:

London : Academic Press, [2024]

Summary:

An Introduction to the Microbiome in Health and Diseases covers the compositional structure and roles of the human microbiome in health and disease.Sections discuss and foundational content, from bench to bedside in microbiology to trigger more in-depth knowledge and provide updated findings on today's hottest topic-the microbiome. The book.

Contents:

Front Cover

An Introduction to the Microbiome in Health and Diseases

Copyright

Contents

Contributors

1 - Microbiome: Introduction and recent advances

Introduction

Microbiome and diseases

The medical relevance of microbiome in the health sector

References

2 - Why the need for microbiome? An updated perspective

Microbiome and Metabolism

Lipid metabolism

Protein metabolism

Microbiome and the environment

Gut microbiome and its metabolites

Microbiome and health

Maternal microbiome and fetal health

Microbiome and metabolic health

Microbiome and cardiovascular health

Microbiome in agriculture and food industry

Relationship between plants and microbiome

Microbiome as a source of novel therapeutics

Conclusion

3 - Procedures for sampling of small and larger samples of microbiome

General overview

Sampling of microbiomes

Fecal microbiome sample collection

Endoscopy

Colonic lavage fluid

Swallowable sampling devices

4 - Microbiome characterization and identification: key emphasis on molecular approaches

Microbiome characterization and identification

Microbiome characterization using nucleic acid-based molecular techniques

Microbiome characterization using omics approaches

Microbiome characterization: the landscape of genome and transcriptome

Microbiome characterization: impact of sequencing and bioinformatics tools

Drawbacks of microbial phenotypic typing

Understanding the microbial genome and sequencing

Understanding microbial diversity

Next-generation sequencing techniques for the microbiome

NGS techniques of microbiomes

16S/18S/ITS rDNA amplicon sequencing.

Metagenomic shotgun sequencing

Roche 454 genome sequencer

Illumina sequencer

Ion Torrent sequencer

PacBio sequencer

Further reading

5 - COVID-19 and microbiome

Covid-19, ACE2, and microbiome

COVID-19 and fecal microbiome transplantation

Microbiome and severity of COVID-19

Microbiome and hypertension in COVID-19

Gut microbiota, immune response, and COVID-19

Neonatal microbiome and COVID-19

Probiotics and COVID-19

Butyrate and COVID-19 management

Gut microbiome and COVID-19-associated gastrointestinal dysfunctions

Summary and conclusion

6 - Introduction to plant microbiome

Determination of plant microbiomes

Environmental factors and microbiomes

Anthropogenic factors and plant microbiomes

Challenges, future perspectives, and conclusion

7 - Introduction to animal microbiome

Rumen and microbiomes

Bird gut and microbiomes

Microbiome in captive and wild animals

Omics in animal microbiome analysis

Animal microbiome

8 - Patents, bioproducts, commercialization, social, ethical, and economic policies on microbiome

Microbiome patents

Metabolic syndrome

Neurological disorders

Agriculture

Gastrointestinal and autoimmune disorders

Cancer immunotherapy

Skin care products

Microbiome biproducts

Social and ethical concerns of microbiome research

Microbiome commercialization

Economic impact on microbiome

9 - Introduction to gut microbiome and epigenetics: Their role in polycystic ovary syndrome pathogenesis

Overview of PCOS

Insulin resistance

Sex hormones

Ovulation and fertility.

Gut microbiota dysbiosis in polycystic ovary syndrome

Normal gut microbiota

Altered gut microbial communities in PCOS

Epigenetics mechanisms and gut microbiota

DNA methylation

Interaction with gut microbiota

Histone modification

Noncoding RNA regulation

Role of diet in microbiota composition and epigenetics

Influence of gut metabolites on epigenetics

Short-chain fatty acids

Polyphenol compounds

Dietary fats

Polyamines

Vitamins

Transgenerational inheritance of PCOS: role of epigenetics

Interplay between epigenetic mechanisms and PCOS

Histone modification and polycystic ovary syndrome

MiRNA expression in polycystic ovary syndrome

DNA methylation and polycystic ovary syndrome

10 - Introduction to epigenetic programming by gut microbiota

Epigenetics of bacterial infections

The process involved in the host acetylation system by bacteria

Regulation of histone acetylation

Gut microbiome and epigenetic regulations

Epigenetic machineries and the microbiome

Gut microbiome: Before or after birth?

Environmental microbiome influences fetal development

Maternal nutrients effect on gut microbiome and epigenetic regulation

Microbiota-immune regulation-epigenetics axis

Diet, gut microbiota, and epigenetic regulation

The involvement of microbiota in immune regulation

11 - Gut microbiota, nutrition, and health: Fundamental and basic principle

Diet and gut microbiota

Dietary fiber

Fat

Protein

Food additives

Polyphenols

Prebiotics

Probiotics

SCFAs, gut-derived and exogenous

Origin, production, and basic functions

Receptors

SCFA receptors as therapeutic targets

SCFAs in Health and Disease

Gut dysbiosis.

Factors causing gut dysbiosis

Health problems linked to gut dysbiosis

Analytical approach for gut microbiota identification

Culture-dependent approach

16S rRNA approach

PCR technique

Fingerprinting technique

Fluorescence in situ hybridization technique

Terminal restriction fragment length polymorphism

Gene (DNA) microarray technique

Sequencing

Cloned 16S rRNA sequencing

Next-generation sequencing

Microbiota applications in health and disease

Gut microbiota and metabolic homeostasis

Immunological functions of microbiome

Index

Back Cover.

Notes:

Description based on publisher supplied metadata and other sources.

Description based on print version record.

ISBN:

9780323911900

9780323914727

0323914721

OCLC:

1431976710