Musculoskeletal Injections Manual : Basics, Techniques and Injectable Agents / edited by Baris Kocaoglu, Lior Laver, Laura de Girolamo, Riccardo Compagnoni.

Format:

Book

Author/Creator:

Kocaoglu, Baris.

Contributor:

Laver, Lior.

Girolamo, Laura de.

Compagnoni, Riccardo.

Series:

Medicine Series

Language:

English

Subjects (All):

Orthopedics.

Sports medicine.

Regenerative medicine.

Orthopaedics.

Sports Medicine.

Regenerative Medicine and Tissue Engineering.

Local Subjects:

Orthopaedics.

Sports Medicine.

Regenerative Medicine and Tissue Engineering.

Physical Description:

1 online resource (213 pages)

Edition:

1st ed. 2024.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2024.

Summary:

This book presents a comprehensive and updated overview of musculoskeletal injections with biologic and non-biologic injectable agents – a new trend of treatment in orthopaedics and sports medicine. This ESSKA book incorporates internal ongoing debates fostered by ESSKA U45 Committee and ESSKA’s Orthobiologics Initiative (ORBIT), which enroll a broad international group of dedicated clinicians and researchers. The topics covered mirror this fast evolving field which ranges from basic science knowledge to treatment options in sports traumatology. Renowned experts in the field examine and critically discuss each aspect, including existing controversies concerning indications and applications as well as the choice between biologic and non-biologic injections. Clear practical indications, subdivided by anatomical region and supported by a wealth of intra-procedural images, are aimed to support young surgeons in the application of musculoskeletal injections. Written by an international panel of clinicians and researchers, active in the field of orthobiology and sports medicine, this manual is an invaluable reference tool for all those involved in injectional therapies and sports traumatology.

Contents:

Intro

Preface

Contents

Part I: Basics of Musculoskeletal Injections

1: Philosophy of Musculoskeletal Injections

1.1 Introduction

1.2 Philosophy of Musculoskeletal Injections

1.3 Conclusion

References

2: The Evidence-Based Medicine for Injection Therapy

2.1 Introduction

2.2 Intra-Articular Injections

2.3 Extra-Articular Injections

2.4 Conclusion

3: Contraindications and Potential Side Effects of Injections

3.1 Introduction

3.2 Intra-Articular Effects

3.3 Surrounding Tissue Effects

3.4 Systemic Effects

3.5 Conclusion

4: Informing Patients

4.1 Possible Complications of Injections

4.2 Obtaining Consent from the Patient

5: Sterilization and Injection Materials

5.1 Introduction

5.2 Injection Equipment

5.3 Preparation of Injection Site

6: Things to Take into Consideration in Injection and Aspiration

6.1 Indication for Treatment

6.2 Settings

6.3 Medical History

6.4 Anatomical Landmarks

6.5 Minimize Risk of Infection

6.6 The Procedure

6.7 Conclusion

7: Postinjection Care and Education

7.1 Introduction

7.2 Immediate Aftercare

7.3 Dressing

7.4 Pressure and Cooling

7.5 Mobilization and Return to Activity

7.6 Postinjection Pain: General Complications

7.7 Postinjection Pain: Local Complications

7.8 Elective Surgery after Injection

7.9 Conclusion

Part II: Non Biologic Agents for Injections

8: Corticosteroids and Local Anesthetics

8.1 Background

8.1.1 Corticosteroids (CS)

8.1.2 Local Anesthetics (LA)

8.2 An Overview of the Indications

8.3 Contraindications

8.4 Complications

8.5 Applications of Corticosteroids and Local Anesthetic in the Knee Joint

8.6 Conclusion

References.

9: Viscosupplementation Agents

9.1 Background

9.2 Mechanism of Action

9.3 Viscosupplementation Agents

9.4 Contraindications and Adverse Events

9.5 Evidence

9.6 Joint-Based Applications

9.6.1 Shoulder

9.6.2 Ankle

9.6.3 Knee

9.6.4 Hip

9.6.5 Hand

9.7 Conclusion

10: Radiosynovectomy

10.1 Introduction

10.2 Indications and Contraindications of Radiosynovectomy

10.3 Informed Concept and Procedure

10.3.1 Joints Specific Approaches and Needle Sizes for RSV

10.3.2 RSV in Rheumatoid Arthritis

10.3.3 RSV in Hemophilia

10.3.4 RSV in Osteoarthritis

10.4 Conclusion

11: Deproteinized Hemoderivative of Calf Blood-Natural Botanical and Mineral Extracts

11.1 Introduction

11.2 Most Used Deproteinized Hemoderivative of Calf Blood-Natural Botanical and Mineral Extracts

11.3 Conclusion

Part III: Ortho-biologic Agents for Injections

12: Orthobiologics: Background

12.1 Introduction

12.2 Types and Effects of Orthobiologics

12.3 Conclusion

13: Platelet-Rich Plasma for Osteoarthritis

13.1 Introduction

13.2 PRP Outcomes for OA

13.3 Application Protocol

13.4 Conclusion

14: Platelet-Rich Plasma Treatment for Meniscal Tears

14.1 The Anatomy of the Menisci

14.2 Meniscal Injuries and Rationale for Use of PRP

14.3 PRP Use for Meniscal Tears: Clinical Data

14.4 Conclusion

15: PRP in Tendinopathy

15.1 Introduction

15.2 Fundamentals of PRP in Tendinopathy

15.3 Role of Leukocytes in the Treatment of Tendinopathies with PRP

15.4 Leukocyte-Rich PRP and Leukocyte-Poor PRP in Tendinopathy

15.5 Importance of the Activation of the Inflammatory Process in the Use of PRP

15.6 Conclusion

16: Platelet-Rich Plasma (PRP) for Rotator Cuff Tears

16.1 Introduction

16.2 Healing Rotator Cuff Injuries with PRP Therapy

16.3 The Effectiveness of PRP for Rotator Cuff Tears

16.3.1 PRP Injections as Isolated Treatment for Rotator Cuff Tears

16.3.2 PRP as an Adjunct to Rotator Cuff Repairs

16.3.3 Effects on the Rotator Cuff's Structural Integrity

16.4 Discussion

16.5 Conclusion

17: Platelet-Rich Plasma Treatment for Muscle Injuries

17.1 Introduction

17.2 Muscle Healing Pathophysiology and Rationale for Using PRP

17.3 Platelet-Rich Plasma for Muscle Injuries: Clinical Experience

17.4 Tips for PRP Use for Muscle Injuries

17.5 Conclusion

18: Bone Marrow Aspirate Concentrates for Knee OA

18.1 Introduction

18.1.1 Safety and Contraindications

18.2 Bone Marrow Tissue

18.2.1 Bone Marrow-Specific Regions

18.2.2 Bone Marrow Niches

18.2.3 Bone Marrow Aspiration

18.3 BMAC Procedural Preparations

18.3.1 BMA Harvesting Sites

18.3.2 Imaging Options

18.3.2.1 Ultrasound

18.3.2.2 Fluoroscopy

18.3.3 Cortical Bone Penetration Options

18.3.4 Anesthetic Considerations

18.3.5 BMA Harvesting Needle Devices

18.3.6 Anticoagulation with Heparin Solution

18.3.7 Extraction/Collection Syringes

18.3.8 BMAC Device Function

18.4 BMC Injection Knee Osteoarthritis

18.4.1 Background

18.4.2 Intra-articular Setup

19: Fat-Derived Orthobiologics for Knee OA

19.1 Introduction

19.1.1 Safety and Contraindications

19.2 Adipose Tissue Background

19.2.1 Adipose Tissue Structure

19.2.2 Adipose-Derived Tissue Stem Cells

19.2.3 Adipose Harvesting Technique Considerations

19.3 Preparation of Minimally Manipulated Products from Adipose Tissue

19.3.1 Adipose Tissue Concentrate.

19.3.2 Micro-fragmented Adipose Tissue (MFAT)

19.3.3 Stromal Vascular Fraction (SVF)

19.3.4 SVF by Enzymatic Digestion

19.4 SVF by Mechanical Disruption

19.5 Adipose Tissue Orthobiological Properties

19.5.1 Immunomodulation

19.5.2 Angiogenesis

19.6 Adipose-Derived Products in Knee Osteoarthritis

20: Autologous Conditioned Serum (ACS)

20.1 Background

20.2 Mechanisms of Action

20.2.1 Inflammatory Modulation

20.2.2 Growth Factors and Cytokines

20.3 Clinical Applications, Indication, and Dosage of Autologous Conditioned Serum Therapy

20.3.1 Osteoarthritis

20.3.2 Tendinopathies

20.3.3 Ligament Injuries

20.3.4 Other Musculoskeletal Conditions

20.3.5 Epidural Peri-radicular Injection for Back Pain

20.4 Application of ACS

20.5 Side Effects and Contraindications

20.6 Future Perspectives and Conclusion

21: Alpha-2-Macroglobulin Concentrate as Orthobiologic in Osteoarthritis

21.1 Introduction

21.1.1 Safety and Contraindications

21.2 General Background A2M Protein Complex

21.2.1 Pharmacological Aspects A2M

21.2.2 Growth Factors, Cytokines, and A2M Application

21.3 Modulating Inflammation and Cartilage Degradation in OA

21.3.1 The Protective Effects of A2M in Synovial Fluid (SF)

21.4 Procedural Steps Producing A2M as Orthobiologic Injectate

21.4.1 Ultrafiltration Process

21.4.2 Clinical A2M Preparation Techniques

21.5 Clinical Data

21.6 Future Directions

Part IV: Injections of Anatomical Regions and Diseases

22: Injections of Anatomical Regions and Diseases: Shoulder

22.1 Sternoclavicular Joint

22.1.1 Anatomy and Biomechanics

22.1.2 Pathologies and Indication for Injections

22.1.3 Appliances

22.1.4 Agents

22.1.5 Injection Technique

22.1.6 Aftercare.

22.2 Acromioclavicular Joint

22.2.1 Anatomy and Biomechanics

22.2.2 Pathologies and Indication for Injections

22.2.3 Appliances

22.2.4 Agents

22.2.5 Injection Technique

22.2.6 Aftercare

22.3 Subacromial Bursa

22.3.1 Anatomy and Biomechanics

22.3.2 Pathologies and Indication for Injections

22.3.3 Appliances

22.3.4 Agents

22.3.5 Injection Technique

22.3.6 Aftercare

22.4 Glenohumeral Joint

22.4.1 Anatomy and Biomechanics

22.4.2 Pathologies and Indication for Injections

22.4.3 Appliances

22.4.4 Agents

22.4.5 Injection Technique

22.4.6 Aftercare

23: Injections of Anatomical Regions and Diseases: Elbow

23.1 Elbow

23.1.1 Anatomy, Diagnosis, and Indications

23.1.2 Type of Injections and Agents

23.1.3 Technique/Tricks/Pitfalls

23.1.4 Aftercare

23.2 Radial Tuberosity (Biceps Tendon Insertion)

23.2.1 Anatomy, Diagnosis, and Indications

23.2.2 Technique/Tricks/Pitfalls

23.2.3 Type of Injections and Agents

23.2.4 Aftercare

23.3 Lateral Epicondylitis

23.3.1 Anatomy, Diagnosis, Indications, and Type of Injection Agents

23.3.2 Technique/Tricks/Pitfalls

23.3.3 Aftercare

23.4 Medial Epicondylitis

23.4.1 Anatomy, Diagnosis, Indications, and Type of Injection Agents

23.4.2 Technique/Tricks/Pitfalls

23.4.3 Aftercare

23.5 Olecranon Bursitis

23.5.1 Anatomy, Diagnosis, Indications, and Type of Injection Agents

23.5.2 Technique/Tricks/Pitfalls

23.5.3 Aftercare

23.6 Conclusions

24: Injections of Anatomical Regions and Diseases: Wrist and Hand

24.1 Wrist Joint

24.1.1 Anatomy

24.1.2 Indication and Diagnosis

24.1.3 Appliances

24.1.4 Agents

24.1.5 Technique/Tricks/Pitfalls

24.1.6 Aftercare

24.2 Distal Radioulnar Joint

24.2.1 Anatomy.

24.2.2 Indication and Diagnosis.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-031-52603-1

OCLC:

1428039088