Cardiac Amyloidosis : Diagnosis and Treatment / edited by Michele Emdin, Giuseppe Vergaro, Alberto Aimo, Marianna Fontana.

Format:

Book

Author/Creator:

Emdin, Michele.

Contributor:

Vergaro, Giuseppe.

Aimo, Alberto.

Fontana, Marianna.

Series:

Medicine Series

Language:

English

Subjects (All):

Medical sciences.

Health Sciences.

Local Subjects:

Health Sciences.

Physical Description:

1 online resource (319 pages)

Edition:

1st ed. 2024.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2024.

Summary:

Cardiac amyloidosis (CA) is caused by the accumulation of amyloid fibrils in the extracellular space of the myocardium, with clinical manifestations including conduction disturbances and heart failure. CA has traditionally been considered a rare disease, lacking effective therapies and with a poor prognosis, but in recent years, increased possibilities for non-invasive diagnosis and greater awareness of the disease have led to the identification of a growing number of cases, challenging the concept of CA as a rare disease. This is why the ability to recognise and manage patients with CA should become part of the core curriculum of cardiologists, but also of internal medicine specialists, neurologists, nephrologists, haematologists, and general practitioners. This book, written by leading experts in the field, will provide the state-of-the-art in the diagnosis and management of CA and will also discuss the latest research developments and future research directions. The volume appears to be a timely one, given the great interest of clinicians and researchers in CA and the exponential increase in publications in recent year, and will be of interest to cardiologists, internal medicine and other disciplines specialists who may encounter patients with CA in their clinical practice, as well as general practitioners.

Contents:

1. Tribute to Claudio Rapezzi

2. Giampaolo Merlini and the Pavia School

3. A brief history of amyloidosis

4. Pathophysiology, classification and epidemiology of amyloidosis

5. Amyloid light chain (AL) amyloidosis

6. Hereditary transthyretin amyloidosis

7. Wild-type ATTR amyloidosis

8. Electrocardiographic patterns

9. Echocardiography: a gatekeeper to diagnosis

10. Cardiovascular magnetic resonance: characterization of myocardial involvement

11. Biomarkers: monoclonal protein and indicators of cardiac damage

12. Plasma transthyretin and its ligands

13. Cardiac Scintigraphy with Bone-Avid Tracers – Old and New Applications

14. PET-CT: a tool for etiological diagnosis

15. The role of tissue biopsy: identification of the amyloid precursor and beyond

16. From red flags to diagnosis

17. Risk prediction and follow-up

18. Differential diagnoses in clinical mimics

19. Applications of Artificial Intelligence in Amyloidosis

20. Treatment of amyloid light-chain amyloidosis

21. Treatment of ATTR amyloidosis: from stabilizers to gene-editing

22. Treatment of cardiac complications

23. Monitoring disease progression and response to disease-modifying treatments

24. Cardiac amyloidosis: open issues and future perspectives.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-031-51757-1

OCLC:

1428976120