Basic Immunology and Its Clinical Application / edited by Mitsuru Matsumoto.

Format:

Book

Author/Creator:

Matsumoto, Mitsuru.

Series:

Advances in Experimental Medicine and Biology, 2214-8019 ; 1444

Language:

English

Subjects (All):

Immunology.

Molecular biology.

Medicine.

Medicine--Research.

Biology--Research.

Biology.

Biochemistry.

Bioinformatics.

Molecular Biology.

Clinical Medicine.

Biomedical Research.

Local Subjects:

Immunology.

Molecular Biology.

Clinical Medicine.

Biomedical Research.

Biochemistry.

Bioinformatics.

Physical Description:

1 online resource (252 pages)

Edition:

1st ed. 2024.

Place of Publication:

Singapore : Springer Nature Singapore : Imprint: Springer, 2024.

Summary:

This book overviews ongoing and upcoming clinical applications of basic immunology. Recent advances in our knowledge of immunology coupled with new technologies have aided in the development of efficient cancer immunotherapy, as well as the control of emerging microorganisms such as SARS-CoV-2. However, knowledge of basic immunology has not been fully utilized even after the discoveries of immune checkpoint inhibition for cancer immunotherapy and the development of mRNA vaccination against SARS-CoV-2. There is still room for improving the clinical application of basic immunology. The book summarizes the achievements in clinical applications of basic immunology and highlights what can be further extended to make immunology a more practical human science. Basic immunology and its clinical applications are two wheels of the same cart in the immunology field, which aids in the development of more efficient cancer immunotherapy and rapid control of infectious diseases against microorganisms, including new viruses and classical toxoplasmosis. The exploration of ongoing and upcoming applications of basic immunology in this book makes it a useful resource for immunologists, physicians, molecular and genome biologists, bioinformaticians, and students in these fields.

Contents:

Part I. From the Bench to the Bedside

1. Novel Insights into the Autoimmunity from the Genetic Approach of the Human Disease

2. Learning the Autoimmune Pathogenesis through the Study of Aire

3. Extrathymic AIRE expressing cells: a historical perspective

4. Autoimmunity Associated with the Misfolded Proteins Complexed with MHC Class II Molecules

5. Regulatory T cells for the Control of Autoimmunity

6. Autoinflammatory Diseases of Men and Mice

7. Nucleoside-Sensing Toll-Like Receptors as Therapeutic Targets for Autoimmune Diseases

Part II.Manipulating the Immune System

8. Development and Function of New Subsets of Innate-Like Lymphocytes and Innate Lymphoid Cells

9. The Molecular Mechanisms and the Functions of New Types of Regulated Cell Death

10. RNA Metabolism Controls Immune Function

Part III Coopting with Microorganisms

11. Development of Orally Ingestible IgA Antibody Drugs to Maintain Symbiosis between Humans and Microorganisms

12. TCR Signals Controlling Both Toxoplasmosis and Cancer

Part IV. Novel Methodologies for the New Era of Immunology

13. Imaging of the CAR-T Cells

14. Development of T-cell Therapy from Multipotent Stem Cell

15. Genetic and Epigenetic Control of Immune Cells

16. HLA Genetics for the Human Diseases.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

9789819997817

981999781X

OCLC:

1427061857